ZFIN is now using GRCz12tu for Genomic Data
Gene
nlgn1
- ID
- ZDB-GENE-090918-1
- Name
- neuroligin 1
- Symbol
- nlgn1 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable neurexin family protein binding activity. Acts upstream of or within sprouting angiogenesis. Predicted to be located in dendrite; plasma membrane; and synapse. Predicted to be active in postsynaptic specialization membrane. Is expressed in several structures, including brain; cardiovascular system; eye; gonad; and swim bladder. Human ortholog(s) of this gene implicated in autistic disorder. Orthologous to human NLGN1 (neuroligin 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 10 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| {Autism, susceptibility to, 20} | 618830 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Alpha/Beta hydrolase fold | Carboxylesterase, type B | Carboxylesterase type B, conserved site | Neuroligin | Neuroligin and Bile salt-activated lipase |
|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M6Z1K4 | InterPro | 847 | |||||
| UniProtKB:D2X2F9 | InterPro | 867 | |||||
| UniProtKB:A0A8M6Z363 | InterPro | 827 | |||||
| UniProtKB:B6EUL6 | InterPro | 847 | |||||
| UniProtKB:A0AC58GNU1 | InterPro | 847 | |||||
| UniProtKB:A0AC58GNU2 | InterPro | 847 | |||||
| UniProtKB:A0AC58GNU6 | InterPro | 847 | |||||
| UniProtKB:A0AC58GNU7 | InterPro | 827 | |||||
| UniProtKB:A0AC58GNU9 | InterPro | 847 | |||||
| UniProtKB:A0AC58GNV1 | InterPro | 847 | |||||
| UniProtKB:A0AC58GNV2 | InterPro | 847 | |||||
| UniProtKB:A0AC58GNV3 | InterPro | 847 | |||||
| UniProtKB:A0AC58GNV4 | InterPro | 867 | |||||
| UniProtKB:A0AC58GNV6 | InterPro | 827 | |||||
| UniProtKB:A0AC58GNV7 | InterPro | 827 | |||||
| UniProtKB:A0AC58GNV8 | InterPro | 847 | |||||
| UniProtKB:A0AC58GNW1 | InterPro | 827 | |||||
| UniProtKB:A0AC58GNW2 | InterPro | 847 | |||||
| UniProtKB:A0AC58GNW8 | InterPro | 827 | |||||
| UniProtKB:A0AC58GNW9 | InterPro | 827 | |||||
| UniProtKB:A0AC58GNX2 | InterPro | 827 | |||||
| UniProtKB:A0AC58GNY3 | InterPro | 847 | |||||
| UniProtKB:A0AC58GNY5 | InterPro | 847 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers