Gene

nlgn1

ID
ZDB-GENE-090918-1
Name
neuroligin 1
Symbol
nlgn1 Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 11 Mapping Details/Browsers
Description
Predicted to have neurexin family protein binding activity and signaling receptor activity. Involved in sprouting angiogenesis. Predicted to localize to cell surface; integral component of plasma membrane; and synapse. Is expressed in several structures, including brain; cardiovascular system; eye; gonad; and swim bladder. Orthologous to human NLGN1 (neuroligin 1).
Genome Resources
Note
None
Expression
All Expression Data
8 figures from 3 publications
Cross-Species Comparison
High Throughput Data
No data available
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With nlgn1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
{Autism, susceptibility to, 20} 618830
Associated With nlgn1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR019819 Carboxylesterase type B, conserved site
Domain IPR002018 Carboxylesterase, type B
Family IPR000460 Neuroligin
Family IPR030022 Neuroligin-1
Family IPR030025 Neuroligin 4
Homologous_superfamily IPR029058 Alpha/Beta hydrolase fold
Domain Details Per Protein
Protein Length Alpha/Beta hydrolase fold Carboxylesterase, type B Carboxylesterase type B, conserved site Neuroligin Neuroligin-1 Neuroligin 4
UniProtKB:A0A0G2L3F9 51
UniProtKB:D0EVW8 847
UniProtKB:E7F5U4 304
UniProtKB:D2X2F9 867
UniProtKB:B6EUL6 847
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations