Gene

slc2a1b

ID
ZDB-GENE-090915-1
Name
solute carrier family 2 member 1b
Symbol
slc2a1b Nomenclature History
Previous Names
  • si:dkey-92f12.1
  • zglut1a (2)
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Exhibits D-glucose transmembrane transporter activity. Involved in sprouting angiogenesis. Predicted to localize to integral component of membrane. Is expressed in several structures, including heart; intestine; kidney; liver; and yolk. Human ortholog(s) of this gene implicated in brain disease (multiple); carbohydrate metabolic disorder; myelomeningocele; obesity; and type 2 diabetes mellitus. Orthologous to human SLC2A1 (solute carrier family 2 member 1).
Genome Resources
Note
None
Expression
All Expression Data
7 figures from 2 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With slc2a1b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
childhood onset GLUT1 deficiency syndrome 2 Alliance GLUT1 deficiency syndrome 2, childhood onset 612126
dystonia 9 Alliance Dystonia 9 601042
idiopathic generalized epilepsy 12 Alliance {Epilepsy, idiopathic generalized, susceptibility to, 12} 614847
GLUT1 deficiency syndrome 1, infantile onset, severe 606777
Stomatin-deficient cryohydrocytosis with neurologic defects 608885
Associated With slc2a1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR005829 Sugar transporter, conserved site
Domain IPR020846 Major facilitator superfamily domain
Family IPR003663 Sugar/inositol transporter
Family IPR005828 Major facilitator, sugar transporter-like
Homologous_superfamily IPR036259 MFS transporter superfamily
Domain Details Per Protein
Protein Length Major facilitator, sugar transporter-like Major facilitator superfamily domain MFS transporter superfamily Sugar/inositol transporter Sugar transporter, conserved site
UniProtKB:A0A2R8Q853 463
UniProtKB:F1R0Q1 489
UniProtKB:A0A2R8QGQ5 456
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations