ZFIN ID: ZDB-GENE-090909-1
Gene Name: tyrosyl-DNA phosphodiesterase 1
Gene Symbol: tdp1
Sequence Ontology ID : SO:0000704

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(Including Attributions)
Location: Chr: 17 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have 3'-tyrosyl-DNA phosphodiesterase activity, double-stranded DNA binding activity, and single-stranded DNA binding activity; predicted to be involved in double-strand break repair and  ...
GENE EXPRESSION
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa6467 Point Mutation Unknown Premature Stop ENU
sa23033 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa42901 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH tdp1 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    spinocerebellar ataxia type 1 with axonal neuropathy Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy 1 607250
    DISEASE ASSOCIATED WITH tdp1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process DNA repair (more)
    Cellular Component nucleus (more)
    Molecular Function phosphoric diester hydrolase activity (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR010347 (1)
  • InterPro:IPR027415 (1)
  • Pfam:PF06087 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA tdp1-201 (1) 2349
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM tdp1 No data available
    MARKER RELATIONSHIPS
    tdp1Contained in: [BAC] DKEY-11L18 (1) (order this), DKEY-104G13 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_695082 (1)
    Genomic GenBank:BX005004 (1) 216131bp Blast at MegaBLAST
    Polypeptide UniProtKB:F8W5U2 (1) 615aa
    Sequence Clusters UniGene:76799 (1)
    Sequence Information (all 11)
    OTHER tdp1 GENE PAGES
  • Alliance (1)
  • Gene:571485 (1)
  • VEGA:OTTDARG00000035132 (1)
  • Ensembl(GRCz11):ENSDARG00000073866 (2)
  • ORTHOLOGY for tdp1 (Chr: 17)
    CITATIONS (14)