ZFIN ID: ZDB-GENE-090821-3
Gene Name: glutamate receptor, metabotropic 1b
Gene Symbol: grm1b    Nomenclature History

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Previous Names: grm1a, si:ch211-278p9.5, zmp:0000000607

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 17 Mapping Details/Browsers
Description: Predicted to have G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential; glutamate receptor activity; and neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration. Predicted to be involved in G protein-coupled glutamate receptor signaling pathway and regulation of glutamatergic synaptic transmission. Predicted to localize to integral component of plasma membrane and postsynaptic density membrane. Is expressed in brain and retinal neural layer. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 13 and spinocerebellar ataxia 44. Orthologous to human GRM1 (glutamate metabotropic receptor 1).
Genome Resources: Alliance (1),  Ensembl(GRCz11):ENSDARG00000098320 (1)
PHENOTYPE No data available
DISEASE ASSOCIATED WITH grm1b HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
autosomal recessive spinocerebellar ataxia 13 Alliance Spinocerebellar ataxia, autosomal recessive 13 614831
spinocerebellar ataxia 44 Alliance Spinocerebellar ataxia 44 617691
DISEASE ASSOCIATED WITH grm1b VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process G protein-coupled receptor signaling pathway (more)
Cellular Component integral component of membrane (more)
Molecular Function G protein-coupled receptor activity (more)
GO Terms (all 13)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA grm1b-202 (1)    Ensembl 844
Browsers: EnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM grm1b No data available
MARKER RELATIONSHIPS
grm1b Contained in: [BAC] CH211-278P9 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
Genomic GenBank:BX296541 (1) 157802 nt
Select Tool
Polypeptide UniProtKB:A0A0R4IU63 (1) 1158 aa
Sequence Information (all 3)
ORTHOLOGY for grm1b ( Chr: 17 )
CITATIONS (18)