Gene

f8

ID
ZDB-GENE-090629-2
Name
coagulation factor VIII, procoagulant component
Symbol
f8 Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 14 Mapping Details/Browsers
Description
Predicted to have copper ion binding activity and oxidoreductase activity. Involved in blood coagulation. Human ortholog(s) of this gene implicated in factor VIII deficiency. Orthologous to human F8 (coagulation factor VIII).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With f8 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
factor VIII deficiency Alliance Hemophilia A 306700
Associated With f8 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR033138 Multicopper oxidases, conserved site
Domain IPR000421 Coagulation factor 5/8 C-terminal domain
Family IPR024715 Coagulation factor 5/8-like
Homologous_superfamily IPR008972 Cupredoxin
Homologous_superfamily IPR008979 Galactose-binding-like domain superfamily
Domain Details Per Protein
Protein Length Coagulation factor 5/8 C-terminal domain Coagulation factor 5/8-like Cupredoxin Galactose-binding-like domain superfamily Multicopper oxidases, conserved site
UniProtKB:A0A0R4INL6 1386
UniProtKB:A0A0R4IBQ7 1674
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations