ZFIN ID: ZDB-GENE-090615-1
Gene Name: double C2-like domains, beta
Gene Symbol: doc2b    Nomenclature History

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 5 Mapping Details/Browsers
Description: Predicted to have Rab GTPase binding activity; calcium ion binding activity; and calcium-dependent phospholipid binding activity. Predicted to be involved in calcium ion-regulated exocytosis of neurotransmitter; intracellular protein transport; and positive regulation of transport. Predicted to localize to membrane. Orthologous to human DOC2B (double C2 domain beta).
Genome Resources: Alliance (1),  Gene:100006713 (1),  Ensembl(GRCz11):ENSDARG00000088293 (2)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa33740 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH doc2b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH doc2b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process calcium ion-regulated exocytosis of neurotransmitter (more)
    Cellular Component membrane (more)
    Molecular Function calcium-dependent phospholipid binding (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA doc2b-201 (1)    Ensembl 773
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM doc2b No data available
    MARKER RELATIONSHIPS
    doc2b Contained in: [BAC] DKEY-195M10 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:XM_009301902 (1)
    Genomic GenBank:CR932980 (1) 253220 nt Blast at MegaBLAST
    Polypeptide UniProtKB:F1QTK2 (1) 648 aa
    Sequence Information (all 29)
    ORTHOLOGY for doc2b ( Chr: 5 )
    CITATIONS (15)