Gene

cnga3a

ID
ZDB-GENE-090611-2
Name
cyclic nucleotide gated channel subunit alpha 3a
Symbol
cnga3a Nomenclature History
Previous Names
  • cnga3
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Predicted to enable cGMP binding activity; intracellular cAMP-activated cation channel activity; and intracellular cGMP-activated cation channel activity. Predicted to act upstream of or within ion transport and transmembrane transport. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in gonad; heart; and nervous system. Human ortholog(s) of this gene implicated in achromatopsia 2 and color blindness. Orthologous to human CNGA3 (cyclic nucleotide gated channel subunit alpha 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Tetreault et al., 2006
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cnga3a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
achromatopsia 2 Alliance Achromatopsia 2 216900
Associated With cnga3a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018488 Cyclic nucleotide-binding, conserved site
Domain IPR000595 Cyclic nucleotide-binding domain
Domain IPR005821 Ion transport domain
Domain IPR032406 Cyclic nucleotide-gated channel, C-terminal leucine zipper domain
Homologous_superfamily IPR014710 RmlC-like jelly roll fold
Homologous_superfamily IPR018490 Cyclic nucleotide-binding-like
Domain Details Per Protein
Protein Length Cyclic nucleotide-binding, conserved site Cyclic nucleotide-binding domain Cyclic nucleotide-binding-like Cyclic nucleotide-gated channel, C-terminal leucine zipper domain Ion transport domain RmlC-like jelly roll fold
UniProtKB:A0A2R8QGC6 704
UniProtKB:F8W5H0 706
UniProtKB:F1QMW6 711
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations