ZFIN ID: ZDB-GENE-090611-2
Gene Name: cyclic nucleotide gated channel subunit alpha 3a
Gene Symbol: cnga3a    Nomenclature History

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Previous Name: cnga3

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 6 Mapping Details/Browsers
Description: Predicted to have cGMP binding activity; intracellular cAMP-activated cation channel activity; and intracellular cGMP-activated cation channel activity. Predicted to be involved in cation transmembrane transport and visual perception. Predicted to localize to the integral component of membrane. Human ortholog(s) of this gene implicated in achromatopsia 2 and color blindness. Is expressed in gonad; heart; and nervous system. Orthologous to human CNGA3 (cyclic nucleotide gated channel subunit alpha 3).
Genome Resources: Alliance (1),  Gene:567242 (1),  Ensembl(GRCz11):ENSDARG00000070726 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hu2132 Point Mutation Unknown Premature Stop ENU
sa20756 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa25344 Point Mutation Unknown Premature Stop ENU
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH cnga3a HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    achromatopsia 2 Alliance Achromatopsia 2 216900
    DISEASE ASSOCIATED WITH cnga3a VIA EXPERIMENTAL MODELS No data available
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR000595 Cyclic nucleotide-binding domain
    Domain IPR005821 Ion transport domain
    Homologous_superfamily IPR014710 RmlC-like jelly roll fold
    Conserved_site IPR018488 Cyclic nucleotide-binding, conserved site
    Homologous_superfamily IPR018490 Cyclic nucleotide-binding-like
    Domain IPR032406 Cyclic nucleotide-gated channel, C-terminal leucine zipper domain
    Family IPR032945 cGMP-gated cation channel alpha-1
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA cnga3a-202 (1)    Ensembl 2807
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM cnga3a No data available
    MARKER RELATIONSHIPS
    cnga3a Contained in: [BAC] DKEY-22G9 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_005166084 (1)
    Genomic GenBank:CR388007 (1) 221983 bp Blast at MegaBLAST
    Polypeptide UniProtKB:F1QMW6 (1) 711 aa
    Sequence Information (all 11)
    ORTHOLOGY for cnga3a ( Chr: 6 )
    CITATIONS (25)