ZFIN ID: ZDB-GENE-090608-3
Gene Name: protocadherin 17
Gene Symbol: pcdh17    Nomenclature History

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 11 Mapping Details/Browsers
Description: Predicted to have calcium ion binding activity. Involved in axon extension; axon guidance; and camera-type eye photoreceptor cell differentiation. Predicted to localize to integral component of plasma membrane. Is expressed in several structures, including brain; immature eye; retina; spinal cord; and spinal cord neural tube. Orthologous to human PCDH17 (protocadherin 17).
Genome Resources: Alliance (1),  Gene:561336 (1),  Ensembl(GRCz11):ENSDARG00000027041 (2)
GENE EXPRESSION
All Expression Data: 21 figures from 4 publications
Wild-type Stages, Structures: Cleavage:16-cell (1.5h-1.75h) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
nkz2 Complex Unknown Unknown CRISPR
sa11699 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa16710 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa38852 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa41876 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa41877 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-pcdh17 1
    MO1-pcdh17 N/A 1
    MO2-pcdh17 N/A 1
    DISEASE ASSOCIATED WITH pcdh17 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH pcdh17 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process axon extension (more)
    Cellular Component integral component of membrane (more)
    Molecular Function calcium ion binding (more)
    GO Terms (all 11)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA pcdh17-201 (1)    Ensembl 5398
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM pcdh17
    Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
    Tg(4xUAS:dnpcdh17-mRFP1,EGFP) UAS EGFPmRFP1pcdh17 Danio rerio 1 1
    Tg(4xUAS:pcdh17-mRFP1,EGFP) UAS EGFPmRFP1pcdh17 Danio rerio 1 1
    Tg2(4xUAS:pcdh17-mRFP1,EGFP) UAS EGFPmRFP1pcdh17 Danio rerio 1 1
    MARKER RELATIONSHIPS
    pcdh17 Contained in: [BAC] CH211-107E16 (1), DKEY-15K16 (1) (order this), DKEYP-71H2 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001160822 (1) 3414 nt
    Genomic GenBank:CR589875 (1) 223329 nt Blast at MegaBLAST
    Polypeptide UniProtKB:C4P342 (1) 1137 aa
    Sequence Information (all 18)
    ORTHOLOGY for pcdh17 ( Chr: 11 )
    CITATIONS (22)