ZFIN ID: ZDB-GENE-090608-1
Gene Name: proprotein convertase subtilisin/kexin type 2
Gene Symbol: pcsk2

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(Including Attributions)
Location: Chr: 13 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 3 figures from 2 publications
Wild-type Stages, Structures: Blastula:Dome (4.33h-4.66h) to Adult (90d-730d, breeding adult)
  brain, eye, gill, gonad (all 15) expand
MUTATIONS AND SEQUENCE TARGETING REAGENTSNo data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH pcsk2 HUMAN ORTHOLOGNo data available
GENE ONTOLOGY
Ontology GO Term
Biological Process proteolysis (more)
Cellular Component integral component of membrane (more)
Molecular Function hydrolase activity (more)
GO Terms (all 9)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000209 (1)
  • InterPro:IPR002884 (1)
  • InterPro:IPR008979 (1)
  • InterPro:IPR009020 (1)
  • InterPro:IPR015500 (1)
  • InterPro:IPR022398 (1)
  • InterPro:IPR023827 (1)
  • InterPro:IPR023828 (1)
  • InterPro:IPR032815 (1)
  • PROSITE:PS00136 (1)
  • PROSITE:PS00137 (1)
  • PROSITE:PS00138 (1)
  • Pfam:PF00082 (1)
  • Pfam:PF01483 (1)
  • Pfam:PF16470 (1)
  • TRANSCRIPTS No data available
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYSNo data available
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM pcsk2 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPSNo data available
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001142266 (1) 1941bp
    Genomic GenBank:CU929052 (1) 129876bp
    Select Tool
    Polypeptide UniProtKB:F1QWV9 (1) 703aa
    Sequence Clusters UniGene:24063 (1)
    Sequence Information (all 9)
    OTHER pcsk2 GENE PAGES
  • Gene:100004460 (1)
  • Ensembl(GRCz10):ENSDARG00000019451 (1)
  • ORTHOLOGY for pcsk2 (Chr: 13)
    Species Symbol Chromosome Accession # Evidence
    Human PCSK2 20
  • Gene:5126
  • OMIM:162151
  • HGNC:8744
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Mouse Pcsk2 2
  • MGI:97512
  • Gene:18549
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (13)