Gene

igfbp6a

ID
ZDB-GENE-090521-1
Name
insulin-like growth factor binding protein 6a
Symbol
igfbp6a Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 11 Mapping Details/Browsers
Description
Predicted to have insulin-like growth factor I binding activity and insulin-like growth factor II binding activity. Predicted to be involved in regulation of insulin-like growth factor receptor signaling pathway. Predicted to localize to extracellular space. Human ortholog(s) of this gene implicated in obesity. Is expressed in several structures, including eye; gill; heart; liver; and pleuroperitoneal region. Orthologous to human IGFBP6 (insulin like growth factor binding protein 6).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
4 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With igfbp6a Human Ortholog
No data available
Associated With igfbp6a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000716 Thyroglobulin type-1
Domain IPR000867 Insulin-like growth factor-binding protein, IGFBP
Family IPR022321 Insulin-like growth factor-binding protein family 1-6, chordata
Family IPR022326 Insulin-like growth factor-binding protein 6
Homologous_superfamily IPR009030 Growth factor receptor cysteine-rich domain superfamily
Homologous_superfamily IPR036857 Thyroglobulin type-1 superfamily
Domain Details Per Protein
Protein Length Growth factor receptor cysteine-rich domain superfamily Insulin-like growth factor-binding protein 6 Insulin-like growth factor-binding protein family 1-6, chordata Insulin-like growth factor-binding protein, IGFBP Thyroglobulin type-1 Thyroglobulin type-1 superfamily
UniProtKB:C4MCP0 194
UniProtKB:A0A2R8QKX9 195
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations