ZFIN ID: ZDB-GENE-090506-9
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Gene Name: structural maintenance of chromosomes 1A
Gene Symbol: smc1a
Sequence Ontology ID : SO:0000704

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Previous Name: sb:eu719

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(Including Attributions)
Location: Chr: 23 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have ATP binding activity and chromatin binding activity; involved in central nervous system development and developmental growth; predicted to localize to the cohesin complex and  ...
GENE EXPRESSION
All Expression Data: 3 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2005 [eu719]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa32449 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa32450 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa44003 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • Targeting reagents:
    PHENOTYPE
    Data: 3 figures from Fazio et al., 2016
    Observed in:
    DISEASE ASSOCIATED WITH smc1a HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Cornelia de Lange syndrome 2 Cornelia de Lange syndrome 2 300590
    DISEASE ASSOCIATED WITH smc1a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process developmental growth (more)
    Cellular Component chromosome (more)
    Molecular Function ATP binding (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR003395 (1)
  • InterPro:IPR010935 (1)
  • InterPro:IPR024704 (1)
  • InterPro:IPR027417 (1)
  • InterPro:IPR029683 (1)
  • InterPro:IPR036277 (1)
    		•
  • Pfam:PF02463 (1)
  • Pfam:PF06470 (1)
    		•
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA smc1a-201 (1) 3745
    Select Tool
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM smc1a No data available
    MARKER RELATIONSHIPS
    smc1aContained in: [BAC] DKEY-23G9 (1) (order this)
    smc1aEncodes: [EST] eu719 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001161631 (1) 3741bp
    Select Tool
    Genomic GenBank:CR354431 (1) 46932bp
    Select Tool
    Polypeptide UniProtKB:E7F0X6 (1) 1232aa
    Select Tool
    Sequence Clusters UniGene:120420 (1)
    Sequence Information (all 9)
    OTHER smc1a GENE PAGES
  • Alliance (1)
  • Gene:559665 (1)
  • VEGA:OTTDARG00000028137 (1)
  • Ensembl(GRCz11):ENSDARG00000055754 (2)
    • ORTHOLOGY for smc1a (Chr: 23)
    CITATIONS (18)