ZFIN Gene: ankhd1

ZFIN ID: ZDB-GENE-090421-1

ZFIN ID: ZDB-GENE-090421-1

Gene Name:

ankyrin repeat and KH domain containing 1

Gene Symbol:

ankhd1 Nomenclature History

Previous Name:

Gene Type:

protein_coding_gene

Location:

Chr: 21 Mapping Details/Browsers

Description:

Predicted to have RNA binding activity. Involved in heart contraction. Predicted to localize to cytoplasm. Orthologous to several human genes including ANKHD1-EIF4EBP3 (ANKHD1-EIF4EBP3 readthrough).

Genome Resources:

Alliance (1), Gene:563327 (1), Ensembl(GRCz11):ENSDARG00000077860 (2)

GENE EXPRESSION
All Expression Data:	Fig. 3 from Baraban et al., 2013
High Throughput Expression:	Expression Atlas (1)

MUTATIONS AND SEQUENCE TARGETING REAGENTS

Allele	Type	Localization	Consequence	Mutagen	Suppliers
la028332Tg	Transgenic Insertion	Unknown	Unknown	DNA	Zebrafish International Resource Center (ZIRC) (order this)
sa10239	Point Mutation	Unknown	Premature Stop	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa23948	Point Mutation	Unknown	Premature Stop	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa23949	Point Mutation	Unknown	Splice Site	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa37324	Point Mutation	Unknown	Premature Stop	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa37325	Point Mutation	Unknown	Splice Site	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)

Sequence Targeting Reagents

Targeting Reagent	Created Alleles	Publications
CRISPR1-ankhd1		2
CRISPR2-ankhd1		2
CRISPR3-ankhd1		2
CRISPR4-ankhd1		2
CRISPR5-ankhd1		2
CRISPR6-ankhd1		2
CRISPR7-ankhd1		2
CRISPR8-ankhd1		2
CRISPR9-ankhd1		2
CRISPR10-ankhd1		2
MO1-ankhd1	N/A	1

PHENOTYPE

Data:	text only from Friedrichs et al., 2009
Observed in:	atrium heart contraction

DISEASE ASSOCIATED WITH ankhd1 HUMAN ORTHOLOG No data available

DISEASE ASSOCIATED WITH ankhd1 VIA EXPERIMENTAL MODELS No data available

GENE ONTOLOGY

Ontology	GO Term
Biological Process	heart contraction (more)
Cellular Component	cytoplasm (more)
Molecular Function	nucleic acid binding (more)

GO Terms (all 5)

PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available

TRANSCRIPTS
Type	Name	Length (nt)	Analysis
mRNA	ankhd1-201 (1)	8535	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Browsers: UCSC, NCBI, Ensembl, ZFIN

INTERACTIONS AND PATHWAYS

ANTIBODIES No data available

PLASMIDS No data available

CONSTRUCTS WITH SEQUENCES FROM ankhd1 No data available

MARKER RELATIONSHIPS

ankhd1 Contained in:

[BAC] CH211-112G7, CH211-123O7

SEQUENCE INFORMATION

Type	Accession #	Length (nt/aa)	Analysis
RNA	RefSeq:NM_001199768 (1)	8455 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Genomic	GenBank:CR354613	179432 nt	Select Tool MegaBLAST Ensembl
Polypeptide	UniProtKB:E9QEX9 (1)	2607 aa	Select Tool ZFIN BLAST SIB BLAST Ensembl Protein Blast

Sequence Information (all 16)

ORTHOLOGY for ankhd1 ( Chr: 21 )

CITATIONS (23)

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