ZFIN ID: ZDB-GENE-090410-3
Gene Name: cholinergic receptor, muscarinic 2b
Gene Symbol: chrm2b    Nomenclature History

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Previous Name: si:dkeyp-8b11.3

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 25 Mapping Details/Browsers
Description: Predicted to have G protein-coupled acetylcholine receptor activity and G protein-coupled serotonin receptor activity. Predicted to be involved in adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway; chemical synaptic transmission; and regulation of smooth muscle contraction. Predicted to localize to dendrite; integral component of plasma membrane; and synapse. Human ortholog(s) of this gene implicated in several diseases, including Chagas disease; asthma; bipolar disorder; heroin dependence; and major depressive disorder. Orthologous to human CHRM2 (cholinergic receptor muscarinic 2).
Genome Resources: Alliance (1),  Gene:555516 (1),  Ensembl(GRCz11):ENSDARG00000116374 (1)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH chrm2b HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH chrm2b VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process G protein-coupled receptor signaling pathway (more)
Cellular Component cell junction (more)
Molecular Function G protein-coupled acetylcholine receptor activity (more)
GO Terms (all 18)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA chrm2b-202 (1)    Ensembl 1401
Browsers: NCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM chrm2b No data available
MARKER RELATIONSHIPS
chrm2b Contained in: [BAC] DKEYP-8B11 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:XM_021470543 (1)
Genomic GenBank:BX546452 (1) 170113 nt
Select Tool
Polypeptide UniProtKB:F8W634 (1) 466 aa
Sequence Information (all 8)
ORTHOLOGY for chrm2b ( Chr: 25 )
CITATIONS (17)