ZFIN ID: ZDB-GENE-090327-1
Gene Name: growth hormone secretagogue receptor b
Gene Symbol: ghsrb    Nomenclature History

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Previous Names: GHS-R2a (1), si:dkey-83f6.2

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 24 Mapping Details/Browsers
Description: Predicted to have growth hormone secretagogue receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Localizes to perinuclear region of cytoplasm and plasma membrane. Is expressed in several structures, including brain; brainstem and spinal white matter; immune system; intestine; and liver. Human ortholog(s) of this gene implicated in obesity. Orthologous to human GHSR (growth hormone secretagogue receptor).
Genome Resources: Alliance (1),  Gene:100332193 (1),  Ensembl(GRCz11):ENSDARG00000057117 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH ghsrb HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Growth hormone deficiency, isolated partial 615925
DISEASE ASSOCIATED WITH ghsrb VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process G protein-coupled receptor signaling pathway (more)
Cellular Component cytoplasm (more)
Molecular Function G protein-coupled receptor activity (more)
GO Terms (all 9)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA ghsrb-201 (1)    Ensembl 1098
Browsers: NCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM ghsrb No data available
MARKER RELATIONSHIPS
ghsrb Contained in: [BAC] DKEY-83F6 (1) (order this)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:XM_002666671 (1)
Genomic GenBank:CU406336 (1) 151564 nt
Select Tool
Polypeptide UniProtKB:E7EZL2 (1) 365 aa
Sequence Information (all 5)
ORTHOLOGY for ghsrb ( Chr: 24 )
CITATIONS (18)