Gene
fastkd2
- ID
- ZDB-GENE-090313-7
- Name
- FAST kinase domains 2
- Symbol
- fastkd2 Nomenclature History
- Previous Names
-
- si:ch211-103i6.5 (1)
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to enable RNA binding activity. Predicted to be involved in mitochondrial RNA processing and regulation of mitochondrial mRNA stability. Predicted to be active in mitochondrial matrix and ribonucleoprotein granule. Used to study combined oxidative phosphorylation deficiency. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency. Orthologous to human FASTKD2 (FAST kinase domains 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Wei et al., 2020
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| combined oxidative phosphorylation deficiency 44 | Alliance | Combined oxidative phosphorylation deficiency 44 | 618855 |
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| combined oxidative phosphorylation deficiency | AB + MO1-fastkd2 | standard conditions | Wei et al., 2020 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | FAST kinase domain-containing | FAST kinase leucine-rich | RAP domain |
|---|---|---|---|---|
|
UniProtKB:A0A8N7UR43
|
652 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
fastkd2-201
(1)
|
Ensembl | 1,887 nt | ||
| mRNA |
fastkd2-202
(1)
|
Ensembl | 1,888 nt |
Interactions and Pathways
No data available
Plasmids
No data available