Gene
dkk1a
- ID
- ZDB-GENE-090313-406
- Name
- dickkopf WNT signaling pathway inhibitor 1a
- Symbol
- dkk1a Nomenclature History
- Previous Names
-
- si:dkeyp-86d6.1
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to have co-receptor binding activity and receptor antagonist activity. Involved in neuromast development and sensory epithelium regeneration. Predicted to localize to extracellular space. Is expressed in anterior segment eye; retinal inner nuclear layer; and retinal outer nuclear layer. Human ortholog(s) of this gene implicated in anodontia. Orthologous to human DKK1 (dickkopf WNT signaling pathway inhibitor 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 11 figures from 10 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR006796 | Dickkopf, N-terminal cysteine-rich |
Domain | IPR047304 | Dickkopf-related protein 1, second cysteine-rich domain |
Domain | IPR048499 | Dickkopf-related protein 1/2/4, C-terminal subdomain 2 |
Domain | IPR048500 | Dickkopf-related protein 1/2/4, C-terminal subdomain 1 |
Family | IPR039863 | Dickkopf related protein 1-4 |
Domain Details Per Protein
Protein | Length | Dickkopf, N-terminal cysteine-rich | Dickkopf-related protein 1/2/4, C-terminal subdomain 1 | Dickkopf-related protein 1/2/4, C-terminal subdomain 2 | Dickkopf related protein 1-4 | Dickkopf-related protein 1, second cysteine-rich domain |
---|---|---|---|---|---|---|
UniProtKB:A0A8M1P605
|
247 | |||||
UniProtKB:A8WGT5
|
255 |
Interactions and Pathways
No data available
Plasmids
No data available