ZFIN ID: ZDB-GENE-090313-230
Gene Name: gamma-aminobutyric acid type A receptor subunit beta1
Gene Symbol: gabrb1    Nomenclature History

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Previous Name: si:dkey-20i10.4

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 13 Mapping Details/Browsers
Description: Predicted to have neurotransmitter receptor activity. Predicted to be involved in several processes, including chemical synaptic transmission; nervous system process; and regulation of membrane potential. Predicted to localize to integral component of plasma membrane; neuron projection; and synapse. Is expressed in brainstem and eye. Human ortholog(s) of this gene implicated in autistic disorder and early infantile epileptic encephalopathy 45. Orthologous to human GABRB1 (gamma-aminobutyric acid type A receptor subunit beta1).
Genome Resources: Alliance (1),  Gene:100331377 (1),  Ensembl(GRCz11):ENSDARG00000076127 (2)
GENE EXPRESSION
All Expression Data: text only from Cocco et al., 2017
Wild-type Stages, Structures: Adult (90d-730d, breeding adult) to Adult (90d-730d, breeding adult)
 
PHENOTYPE No data available
DISEASE ASSOCIATED WITH gabrb1 HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
early infantile epileptic encephalopathy 45 Alliance Epileptic encephalopathy, early infantile, 45 617153
DISEASE ASSOCIATED WITH gabrb1 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process ion transmembrane transport (more)
Cellular Component integral component of membrane (more)
Molecular Function extracellular ligand-gated ion channel activity (more)
GO Terms (all 20)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA gabrb1-201 (1)    Ensembl 6580
Browsers: NCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM gabrb1 No data available
MARKER RELATIONSHIPS
gabrb1 Contained in: [BAC] CH73-235J12 (1), DKEY-20I10 (1) (order this)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:XM_002664133 (1)
Genomic GenBank:CT025771 (1) 190607 nt
Select Tool
Polypeptide UniProtKB:F1QPW7 (1) 484 aa
Sequence Information (all 10)
ORTHOLOGY for gabrb1 ( Chr: 13 )
CITATIONS (20)