ZFIN ID: ZDB-GENE-090313-224
Gene Name: prolyl endopeptidase like
Gene Symbol: prepl    Nomenclature History

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Previous Name: si:dkey-202m23.1

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 13 Mapping Details/Browsers
Description: Predicted to have serine-type endopeptidase activity and serine-type exopeptidase activity. Predicted to be involved in proteolysis. Predicted to localize to Golgi apparatus and cytoskeleton. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome 22. Orthologous to human PREPL (prolyl endopeptidase like).
Genome Resources: Alliance (1),  Gene:796680 (1),  Ensembl(GRCz11):ENSDARG00000017853 (1)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la012272Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa22235 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH prepl HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    congenital myasthenic syndrome 22 Alliance Myasthenic syndrome, congenital, 22 616224
    DISEASE ASSOCIATED WITH prepl VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process proteolysis (more)
    Cellular Component cytoskeleton (more)
    Molecular Function serine-type endopeptidase activity (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA prepl-201 (1)    Ensembl 2379
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM prepl No data available
    MARKER RELATIONSHIPS
    prepl Contained in: [BAC] DKEY-202M23 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001145616 (1) 2251 nt
    Genomic GenBank:CT030019 (1) 69400 nt
    Select Tool
    Polypeptide UniProtKB:B8JJX2 (1) 692 aa
    Sequence Information (all 8)
    ORTHOLOGY for prepl ( Chr: 13 )
    CITATIONS (17)