ZFIN ID: ZDB-GENE-090313-222
Gene Name: Rho guanine nucleotide exchange factor (GEF) 10-like b
Gene Symbol: arhgef10lb    Nomenclature History

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Previous Names: arhgef10l, si:dkey-1c11.5

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 23 Mapping Details/Browsers
Description: Predicted to have Rho guanyl-nucleotide exchange factor activity. Predicted to be involved in actin cytoskeleton organization and positive regulation of stress fiber assembly. Human ortholog(s) of this gene implicated in ovarian endometrial cancer and ovarian serous carcinoma. Orthologous to human ARHGEF10L (Rho guanine nucleotide exchange factor 10 like).
Genome Resources: Alliance (1),  Gene:567649 (1),  Ensembl(GRCz11):ENSDARG00000074244 (1)
GENE EXPRESSION No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH arhgef10lb HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH arhgef10lb VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process actin cytoskeleton organization (more)
Molecular Function guanyl-nucleotide exchange factor activity (more)
GO Terms (all 4)
PROTEIN FAMILIES, DOMAINS AND SITES
Type InterPro ID Name
Domain IPR000219 Dbl homology (DH) domain
Homologous_superfamily IPR011993 PH-like domain superfamily
Homologous_superfamily IPR015943 WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily IPR035899 Dbl homology (DH) domain superfamily
Homologous_superfamily IPR036322 WD40-repeat-containing domain superfamily
Family IPR039919 Rho guanine nucleotide exchange factor 10/17
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA arhgef10lb-202 (1)    Ensembl 3114
arhgef10lb-203 (1)    Ensembl 867
Browsers: NCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM arhgef10lb No data available
MARKER RELATIONSHIPS
arhgef10lb Contained in: [BAC] DKEY-1C11 (1) (order this)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:XM_009296888 (1)
Genomic GenBank:CR847529 (1) 158776 bp
Select Tool
Polypeptide UniProtKB:F1R7Q3 (1) 1037 aa
Sequence Information (all 29)
ORTHOLOGY for arhgef10lb ( Chr: 23 )
CITATIONS (17)