Gene

slc4a11

ID
ZDB-GENE-090313-183
Name
solute carrier family 4 member 11
Symbol
slc4a11 Nomenclature History
Previous Names
  • si:dkey-12j14.4
Type
protein_coding_gene
Location
Chr: 13 Mapping Details/Browsers
Description
Predicted to have transmembrane transporter activity. Predicted to be involved in ion homeostasis and transmembrane transport. Predicted to localize to basolateral plasma membrane. Is expressed in several structures, including eye; gill; heart; muscle; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in Fuchs' endothelial dystrophy; congenital hereditary endothelial dystrophy of cornea; and corneal dystrophy-perceptive deafness syndrome. Orthologous to human SLC4A11 (solute carrier family 4 member 11).
Genome Resources
Note
None
Expression
All Expression Data
from Lee et al., 2011
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With slc4a11 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
congenital hereditary endothelial dystrophy of cornea Alliance Corneal endothelial dystrophy, autosomal recessive 217700
corneal dystrophy-perceptive deafness syndrome Alliance Corneal endothelial dystrophy and perceptive deafness 217400
Fuchs' endothelial dystrophy Alliance Corneal dystrophy, Fuchs endothelial, 4 613268
Associated With slc4a11 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR002178 PTS EIIA type-2 domain
Domain IPR011531 Bicarbonate transporter, C-terminal
Family IPR003020 Bicarbonate transporter, eukaryotic
Homologous_superfamily IPR016152 Phosphotransferase/anion transporter
Domain Details Per Protein
Protein Length Bicarbonate transporter, C-terminal Bicarbonate transporter, eukaryotic Phosphotransferase/anion transporter PTS EIIA type-2 domain
UniProtKB:A0A0R4IZS1 818
UniProtKB:F6NGR0 846
UniProtKB:E9QBH5 782
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations