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Gene

trim2b

ID
ZDB-GENE-090312-70
Name
tripartite motif containing 2b
Symbol
trim2b Nomenclature History
Previous Names
  • si:dkeyp-75b4.11
  • trim2like (1)
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process and protein polyubiquitination. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 2R. Orthologous to human TRIM2 (tripartite motif containing 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With trim2b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Charcot-Marie-Tooth disease type 2R Alliance Charcot-Marie-Tooth disease, type 2R 615490
Associated With trim2b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000315 B-box-type zinc finger
Domain IPR003649 B-box, C-terminal
Homologous_superfamily IPR011042 Six-bladed beta-propeller, TolB-like
Homologous_superfamily IPR013783 Immunoglobulin-like fold
Homologous_superfamily IPR014756 Immunoglobulin E-set
Repeat IPR001258 NHL repeat
Repeat IPR001298 Filamin/ABP280 repeat
Repeat IPR013017 NHL repeat, subgroup
Repeat IPR017868 Filamin/ABP280 repeat-like
Domain Details Per Protein
Protein Length B-box, C-terminal B-box-type zinc finger Filamin/ABP280 repeat Filamin/ABP280 repeat-like Immunoglobulin E-set Immunoglobulin-like fold NHL repeat NHL repeat, subgroup Six-bladed beta-propeller, TolB-like
UniProtKB:B8A5M1 669
UniProtKB:A0A2R8QCG3 638
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations