ZFIN ID: ZDB-GENE-090312-209
Gene Name: TOX high mobility group box family member 3
Gene Symbol: tox3    Nomenclature History

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Previous Name: si:dkey-117i6.1 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 7 Mapping Details/Browsers
Description: Predicted to have DNA binding activity. Predicted to localize to the nucleus. Is expressed in rhombomere 3 and rhombomere 5. Orthologous to human TOX3 (TOX high mobility group box family member 3).
Genome Resources: Alliance (1),  Gene:555286 (1),  Ensembl(GRCz11):ENSDARG00000073957 (2)
GENE EXPRESSION
All Expression Data: 5 figures from 2 publications
Wild-type Stages, Structures: Segmentation:10-13 somites (14.0h-16.0h) to Segmentation:10-13 somites (14.0h-16.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa9897 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa15483 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa34124 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-tox3 N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH tox3 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH tox3 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 2)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR009071 High mobility group box domain
    Homologous_superfamily IPR036910 High mobility group box domain superfamily
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA tox3-201 (1)    Ensembl 4118
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM tox3 No data available
    MARKER RELATIONSHIPS
    tox3 Contained in: [BAC] DKEY-117I6 (1) (order this), DKEY-181O16 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_005169018 (1) 3816 bp
    Genomic GenBank:CR394544 (1) 194826 bp
    Select Tool
    Polypeptide UniProtKB:E7FAU5 (1) 587 aa
    Sequence Information (all 16)
    ORTHOLOGY for tox3 ( Chr: 7 )
    CITATIONS (20)