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ZIRC
ZFIN ID: ZDB-GENE-090312-201
Gene Name: nephronectin a
Gene Symbol: npnta    Nomenclature History

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Previous Names: npnt, si:ch211-202n8.2

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 1 Mapping Details/Browsers
Description: Predicted to have calcium ion binding activity. Involved in atrioventricular valve development and heart trabecula formation. Predicted to localize to the membrane. Used to study proteinuria. Is expressed in several structures, including digestive system; endoderm; head; heart; and tail bud. Orthologous to human NPNT (nephronectin).
Genome Resources: Alliance (1),  Gene:563273 (1),  Ensembl(GRCz11):ENSDARG00000018721 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la013711Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la013712Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la013713Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la028177Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa15583 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa19582 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa19583 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa19584 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • zko970a Small Deletion Unknown Unknown CRISPR
    zko970b Insertion Unknown Unknown CRISPR
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-npnta 1
    MO1-npnta N/A 1
    MO2-npnta N/A 2
    MO3-npnta N/A 1
    DISEASE ASSOCIATED WITH npnta HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH npnta VIA EXPERIMENTAL MODELS
    Human Disease Fish Conditions Citations
    proteinuria WT + MO2-npnta standard conditions Müller-Deile et al., 2017
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process atrioventricular valve development (more)
    Cellular Component membrane (more)
    Molecular Function calcium ion binding (more)
    GO Terms (all 4)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA npnt-201 (1)    Ensembl 2441
    npnt-202 (1)    Ensembl 431
    ncRNA npnt-003 (1) 547
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM npnta No data available
    MARKER RELATIONSHIPS
    npnta Contained in: [BAC] CH211-202N8 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001145580 (1) 2018 bp
    Genomic GenBank:BX537118 (1) 197161 bp
    Select Tool
    Polypeptide UniProtKB:H2DL88 (1) 633 aa
    Sequence Clusters UniGene:113684 (1)
    Sequence Information (all 19)
    ORTHOLOGY for npnta ( Chr: 1 )
    CITATIONS (21)