ZFIN ID: ZDB-GENE-090312-199
Gene Name: N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
Gene Symbol: ndst3    Nomenclature History

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Previous Name: si:ch211-152j23.1

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 1 Mapping Details/Browsers
Description: Predicted to have [heparan sulfate]-glucosamine N-sulfotransferase activity and deacetylase activity. Predicted to be involved in heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process. Predicted to localize to Golgi apparatus. Is expressed in central nervous system; dermis; neural rod; olfactory placode; and pectoral fin. Orthologous to several human genes including NDST4 (N-deacetylase and N-sulfotransferase 4).
Genome Resources: Alliance (1),  Gene:100317129 (1),  Ensembl(GRCz11):ENSDARG00000041776 (2)
Note: ndst3 is orthologous to NDST3 and NDST4. There appears to have been a tandem duplication after the divergence of ray-finned and lobe-finned fishes.
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa1553 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa19474 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa19475 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa39597 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • zko390a Indel Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-ndst3 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH ndst3 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH ndst3 VIA EXPERIMENTAL MODELS No data available
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA ndst3-201 (1)    Ensembl 3481
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM ndst3 No data available
    MARKER RELATIONSHIPS
    ndst3 Contained in: [BAC] CH211-152J23 (1), DKEY-21O10 (order this), DKEY-47A21 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:XM_009307604 (1)
    Genomic GenBank:BX248500 (1) 230877 nt Blast at MegaBLAST
    Polypeptide UniProtKB:E7F825 (1) 874 aa
    Sequence Information (all 20)
    ORTHOLOGY for ndst3 ( Chr: 1 )
    CITATIONS (23)