ZFIN ID: ZDB-GENE-090312-153
Gene Name: LIM and calponin homology domains 1a
Gene Symbol: limch1a    Nomenclature History

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Previous Name: si:ch211-157h5.2

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 1 Mapping Details/Browsers
Description: Predicted to have myosin II head/neck binding activity. Predicted to be involved in positive regulation of stress fiber assembly and regulation of focal adhesion assembly. Predicted to colocalize with myosin II complex. Is expressed in trunk vasculature. Orthologous to human LIMCH1 (LIM and calponin homology domains 1).
Genome Resources: Alliance (1),  Gene:561940 (1),  Ensembl(GRCz11):ENSDARG00000074275 (2)
GENE EXPRESSION
All Expression Data: Fig. S1 from Kartopawiro et al., 2014
Wild-type Stages, Structures: Hatching:Long-pec (48.0h-60.0h) to Hatching:Long-pec (48.0h-60.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa15501 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa16015 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa31201 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa44508 Point Mutation Unknown Unknown ENU
    zko360b Small Deletion Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-limch1a 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH limch1a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH limch1a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process actomyosin structure organization (more)
    Cellular Component COLOCALIZES_WITH   myosin II complex (more)
    Molecular Function actin binding (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA limch1a-201 (1)    Ensembl 3454
    ncRNA limch1a-002 (1)    Ensembl 931
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM limch1a No data available
    MARKER RELATIONSHIPS
    limch1a Contained in: [BAC] CH211-157H5 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001145577 (1) 3454 nt
    Genomic GenBank:BX323984 (1) 177080 nt
    Select Tool
    Polypeptide UniProtKB:B8A4X7 (1) 1019 aa
    Sequence Information (all 19)
    ORTHOLOGY for limch1a ( Chr: 1 )
    CITATIONS (17)