Gene
neurl1aa
- ID
- ZDB-GENE-090311-3
- Name
- neuralized E3 ubiquitin protein ligase 1Aa
- Symbol
- neurl1aa Nomenclature History
- Previous Names
-
- neurl1a
- neurl
- neurla
- si:dkey-82d4.3
- zgc:153971 (1)
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in negative regulation of Notch signaling pathway. Predicted to be located in dendrite; perikaryon; and perinuclear region of cytoplasm. Predicted to be active in plasma membrane and postsynaptic density. Orthologous to human NEURL1 (neuralized E3 ubiquitin protein ligase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Sinner et al., 2014
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | B30.2/SPRY domain superfamily | Neuralized | Neuralized homology repeat (NHR) domain | Zinc finger, RING/FYVE/PHD-type | Zinc finger, RING-type |
|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9PHX8 | InterPro | 572 | |||||
| UniProtKB:A0JML9 | InterPro | 558 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
neurl1aa-201
(1)
|
Ensembl | 3,866 nt |
Interactions and Pathways
No data available
Plasmids
No data available