Gene

rasgrf1

ID
ZDB-GENE-090311-28
Name
Ras protein specific guanine nucleotide releasing factor 1
Symbol
rasgrf1 Nomenclature History
Previous Names
  • si:ch211-234p18.3
Type
protein_coding_gene
Location
Chr: 18 Mapping Details/Browsers
Description
Predicted to have guanyl-nucleotide exchange factor activity. Predicted to be involved in regulation of Rho protein signal transduction and small GTPase mediated signal transduction. Orthologous to human RASGRF1 (Ras protein specific guanine nucleotide releasing factor 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With rasgrf1 Human Ortholog
No data available
Associated With rasgrf1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Binding_site IPR000048 IQ motif, EF-hand binding site
Conserved_site IPR001331 Guanine-nucleotide dissociation stimulator, CDC24, conserved site
Conserved_site IPR019804 Ras guanine-nucleotide exchange factor, conserved site
Domain IPR000219 Dbl homology (DH) domain
Domain IPR000651 Ras-like guanine nucleotide exchange factor, N-terminal
Domain IPR001849 Pleckstrin homology domain
Domain IPR001895 Ras guanine-nucleotide exchange factors catalytic domain
Family IPR008937 Ras-like guanine nucleotide exchange factor
Family IPR030745 Ras-specific guanine nucleotide-releasing factor 1
Homologous_superfamily IPR011993 PH-like domain superfamily
Homologous_superfamily IPR023578 Ras guanine nucleotide exchange factor domain superfamily
Homologous_superfamily IPR035899 Dbl homology (DH) domain superfamily
Homologous_superfamily IPR036964 Ras guanine-nucleotide exchange factor catalytic domain superfamily
Domain Details Per Protein
Protein Length Dbl homology (DH) domain Dbl homology (DH) domain superfamily Guanine-nucleotide dissociation stimulator, CDC24, conserved site IQ motif, EF-hand binding site PH-like domain superfamily Pleckstrin homology domain Ras guanine-nucleotide exchange factor catalytic domain superfamily Ras guanine-nucleotide exchange factor, conserved site Ras guanine nucleotide exchange factor domain superfamily Ras guanine-nucleotide exchange factors catalytic domain Ras-like guanine nucleotide exchange factor Ras-like guanine nucleotide exchange factor, N-terminal Ras-specific guanine nucleotide-releasing factor 1
UniProtKB:E7F7V2 1256
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations