ZFIN ID: ZDB-GENE-090311-19
Gene Name: LPS-responsive vesicle trafficking, beach and anchor containing
Gene Symbol: lrba
Sequence Ontology ID : SO:0000704

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Previous Name: si:dkey-257n17.3 (1)

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(Including Attributions)
Location: Chr: 1 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Orthologous to human LRBA (LPS responsive beige-like anchor protein).
GENE EXPRESSION
All Expression Data: Fig. 2 from Sribudiani et al., 2018
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Larval:Day 4 (96.0h-120.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa780 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa25575 Point Mutation Unknown Premature Stop ENU
    sa32677 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa38265 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa39611 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa39612 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE
    Data: Fig. 2 from Sribudiani et al., 2018
    Observed in:
    DISEASE ASSOCIATED WITH lrba HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    common variable immunodeficiency Immunodeficiency, common variable, 8, with autoimmunity 614700
    DISEASE ASSOCIATED WITH lrba VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY No data available
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000409 (1)
  • InterPro:IPR001680 (1)
  • InterPro:IPR010508 (1)
  • InterPro:IPR011989 (1)
  • InterPro:IPR013320 (1)
  • InterPro:IPR015943 (1)
  • InterPro:IPR016024 (1)
  • InterPro:IPR023362 (1)
  • InterPro:IPR031570 (1)
  • InterPro:IPR036322 (1)
  • InterPro:IPR036372 (1)
  • PROSITE:PS50197 (1)
  • PROSITE:PS51783 (1)
  • Pfam:PF02138 (1)
  • Pfam:PF06469 (1)
  • Pfam:PF14844 (1)
  • Pfam:PF15787 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA lrba-201 (1) 1145
    lrba-202 (1) 5550
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM lrba No data available
    MARKER RELATIONSHIPS
    lrbaContained in: [BAC] DKEY-40H17 (1) (order this), DKEY-237H21 (1) (order this), DKEY-257N17 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    Genomic GenBank:BX005068 (1) 215007bp Blast at MegaBLAST
    Polypeptide UniProtKB:A0A286Y8V9 (1) 2861aa
    Sequence Information (all 6)
    OTHER lrba GENE PAGES
  • Alliance (1)
  • VEGA:OTTDARG00000031829 (1)
  • Ensembl(GRCz11):ENSDARG00000031108 (2)
  • ORTHOLOGY for lrba (Chr: 1)
    CITATIONS (16)