Gene

mapk8ip3

ID
ZDB-GENE-090303-6
Name
mitogen-activated protein kinase 8 interacting protein 3
Symbol
mapk8ip3 Nomenclature History
Previous Names
  • jip3 (1)
  • JNK-interacting protein 3 (1)
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Predicted to have JUN kinase binding activity; kinesin binding activity; and signaling adaptor activity. Involved in regulation of JNK cascade and retrograde axonal transport. Predicted to localize to cytoplasm. Is expressed in central nervous system; peripheral nervous system; and posterior lateral line ganglion. Orthologous to human MAPK8IP3 (mitogen-activated protein kinase 8 interacting protein 3).
Genome Resources
Note
None
Expression
All Expression Data
Fig. 1 from Drerup et al., 2013
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
11 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With mapk8ip3 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Neurodevelopmental disorder with or without variable brain abnormalities 618443
Associated With mapk8ip3 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR019143 JNK/Rab-associated protein-1, N-terminal
Domain IPR032486 JNK-interacting protein, leucine zipper II
Domain IPR034743 RH1 domain
Domain IPR034744 RH2 domain
Family IPR039911 JNK-interacting protein 3/4
Homologous_superfamily IPR015943 WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily IPR036322 WD40-repeat-containing domain superfamily
Domain Details Per Protein
Protein Length JNK-interacting protein 3/4 JNK-interacting protein, leucine zipper II JNK/Rab-associated protein-1, N-terminal RH1 domain RH2 domain WD40-repeat-containing domain superfamily WD40/YVTN repeat-like-containing domain superfamily
UniProtKB:E9QGL9 1313
UniProtKB:L7RKJ8 1299
UniProtKB:A0A0R4IDR7 1299
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations