Gene

ap2a1

ID
ZDB-GENE-090302-2
Name
adaptor related protein complex 2 subunit alpha 1
Symbol
ap2a1 Nomenclature History
Previous Names
  • fa95c07
  • si:ch211-195b15.3
  • wu:fa95c07 (1)
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Predicted to have clathrin adaptor activity. Involved in dorsal/ventral axis specification and hematopoietic stem cell differentiation. Predicted to localize to AP-2 adaptor complex. Orthologous to human AP2A1 (adaptor related protein complex 2 subunit alpha 1).
Genome Resources
Note
None
Expression
All Expression Data
1 figure from Umasankar et al., 2012
Cross-Species Comparison
High Throughput Data
No data available
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
4 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ap2a1 Human Ortholog
No data available
Associated With ap2a1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR002553 Clathrin/coatomer adaptor, adaptin-like, N-terminal
Domain IPR003164 Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain
Domain IPR008152 Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain
Family IPR017104 Adaptor protein complex AP-2, alpha subunit
Homologous_superfamily IPR009028 Coatomer/calthrin adaptor appendage, C-terminal subdomain
Homologous_superfamily IPR011989 Armadillo-like helical
Homologous_superfamily IPR012295 TBP domain superfamily
Homologous_superfamily IPR013041 Clathrin adaptor, appendage, Ig-like subdomain superfamily
Homologous_superfamily IPR016024 Armadillo-type fold
Domain Details Per Protein
Protein Length Adaptor protein complex AP-2, alpha subunit Armadillo-like helical Armadillo-type fold Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain Clathrin adaptor, appendage, Ig-like subdomain superfamily Clathrin/coatomer adaptor, adaptin-like, N-terminal Coatomer/calthrin adaptor appendage, C-terminal subdomain TBP domain superfamily
UniProtKB:X1WD71 959
UniProtKB:X1WFD2 129
UniProtKB:X1WC51 263
UniProtKB:X1WHT2 305
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Citations