ZFIN ID: ZDB-GENE-090128-4
Gene Name: limb development membrane protein 1
Gene Symbol: lmbr1    Nomenclature History

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Previous Name: im:7156444

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 7 Mapping Details/Browsers
Description: Predicted to have transmembrane signaling receptor activity. Predicted to be involved in signal transduction. Predicted to localize to integral component of plasma membrane. Human ortholog(s) of this gene implicated in Laurin-Sandrow syndrome; acheiropody; and hypoplastic or aplastic tibia with polydactyly. Orthologous to human LMBR1 (limb development membrane protein 1).
Genome Resources: Alliance (1),  Gene:557300 (1),  Ensembl(GRCz11):ENSDARG00000024092 (1)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la016121Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa34140 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa40974 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH lmbr1 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    acheiropody Alliance Acheiropody 200500
    hypoplastic or aplastic tibia with polydactyly Alliance Hypoplastic or aplastic tibia with polydactyly 188740
    Laurin-Sandrow syndrome Alliance Laurin-Sandrow syndrome 135750
    polydactyly Alliance Polydactyly, preaxial type II 174500
    Triphalangeal thumb, type I 174500
    Triphalangeal thumb-polysyndactyly syndrome 174500
    syndactyly type 4 Alliance Syndactyly, type IV 186200
    DISEASE ASSOCIATED WITH lmbr1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process signal transduction (more)
    Cellular Component integral component of membrane (more)
    Molecular Function transmembrane signaling receptor activity (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA lmbr1-001 (1) 4908
    Browsers: NCBI
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM lmbr1 No data available
    MARKER RELATIONSHIPS
    lmbr1 Contained in: [BAC] CH211-211A4 (1), CH211-266O5 (1)
    lmbr1 Encodes: [EST] IMAGE:7156444 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001252604 (1) 1596 nt
    Genomic GenBank:BX247878 (1) 190715 nt
    Select Tool
    Polypeptide UniProtKB:A0A0R4IR97 (1) 490 aa
    Sequence Information (all 19)
    ORTHOLOGY for lmbr1 ( Chr: 7 )
    CITATIONS (20)