ZFIN ID: ZDB-GENE-090107-3
Gene Name: insulin-like growth factor binding protein 2b
Gene Symbol: igfbp2b
Sequence Ontology ID : SO:0000704

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Previous Names: igfbp2a, si:ch211-2k18.3 (1)

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(Including Attributions)
Location: Chr: 9 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Exhibits insulin-like growth factor I binding activity; involved in negative regulation of developmental growth; predicted to localize to the extracellular space; orthologous to human IGFBP2 (insulin  ...
GENE EXPRESSION
All Expression Data: Fig. 4 from Zhou et al., 2008
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la027039Tg Transgenic Insertion Unknown Unknown DNA
sa8707 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH igfbp2b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH igfbp2b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process negative regulation of developmental growth (more)
    Cellular Component extracellular region (more)
    Molecular Function insulin-like growth factor binding (more)
    GO Terms (all 12)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000716 (1)
  • InterPro:IPR000867 (1)
  • InterPro:IPR009030 (1)
  • InterPro:IPR009168 (1)
  • InterPro:IPR012210 (1)
  • InterPro:IPR017891 (1)
  • InterPro:IPR022321 (1)
  • InterPro:IPR036857 (1)
  • PROSITE:PS00222 (1)
  • PROSITE:PS51162 (1)
  • PROSITE:PS51323 (1)
  • Pfam:PF00086 (1)
  • Pfam:PF00219 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA igfbp2b-001 (1) 1208
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM igfbp2b No data available
    MARKER RELATIONSHIPS
    igfbp2bContained in: [BAC] CH211-2K18 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001126464 (1)
    Genomic GenBank:BX005007 (1) 153130bp
    Select Tool
    Polypeptide UniProtKB:B3F211 (1) 265aa
    Sequence Clusters UniGene:111469 (1)
    Sequence Information (all 11)
    OTHER igfbp2b GENE PAGES
  • Alliance (1)
  • Gene:798920 (1)
  • VEGA:OTTDARG00000026127 (1)
  • Ensembl(GRCz11):ENSDARG00000031422 (2)
  • ORTHOLOGY for igfbp2b (Chr: 9)
    CITATIONS (33)