ZFIN ID: ZDB-GENE-081218-1
Gene Name: phosphofurin acidic cluster sorting protein 2
Gene Symbol: pacs2    Nomenclature History

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 13 Mapping Details/Browsers
Description: Predicted to have ion channel binding activity. Predicted to be involved in protein localization to plasma membrane. Human ortholog(s) of this gene implicated in early infantile epileptic encephalopathy 66. Orthologous to human PACS2 (phosphofurin acidic cluster sorting protein 2).
Genome Resources: Alliance (1),  Gene:794778 (1),  Ensembl(GRCz11):ENSDARG00000078185 (2)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la027450Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa31948 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa35555 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-pacs2 N/A 1
    PHENOTYPE
    Data: Fig. S4 from Fu et al., 2008
    Observed in:
    DISEASE ASSOCIATED WITH pacs2 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    early infantile epileptic encephalopathy 66 Alliance Epileptic encephalopathy, early infantile, 66 618067
    DISEASE ASSOCIATED WITH pacs2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process protein localization to plasma membrane (more)
    Molecular Function ion channel binding (more)
    GO Terms (all 2)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA pacs2-201 (1)    Ensembl 2637
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM pacs2 No data available
    MARKER RELATIONSHIPS
    pacs2 Contained in: [BAC] CH73-92F12 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001122751 (1) 2637 nt
    Genomic GenBank:FP103009 (1) 119068 nt
    Select Tool
    Polypeptide UniProtKB:B1NJ27 (1) 878 aa
    Sequence Information (all 16)
    ORTHOLOGY for pacs2 ( Chr: 13 )
    CITATIONS (17)