ZFIN ID: ZDB-GENE-081113-4
Gene Name: actinin, alpha 1
Gene Symbol: actn1    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Name:

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 13 Mapping Details/Browsers
Description: Predicted to have actin filament binding activity and calcium ion binding activity. Predicted to be involved in actin crosslink formation and actin filament bundle assembly. Is expressed in several structures, including head muscle; intestine; nervous system; ovary; and ventral intermandibularis anterior. Human ortholog(s) of this gene implicated in platelet-type bleeding disorder 15. Orthologous to human ACTN1 (actinin alpha 1).
Genome Resources: Alliance (1),  Gene:560400 (1),  Ensembl(GRCz11):ENSDARG00000007219 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH actn1 HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
platelet-type bleeding disorder 15 Alliance Bleeding disorder, platelet-type, 15 615193
DISEASE ASSOCIATED WITH actn1 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process actin crosslink formation (more)
Molecular Function actin binding (more)
GO Terms (all 5)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
aberrant processed transcript actn1-202 (1)    Ensembl 3658
actn1-203 (1)    Ensembl 993
mRNA actn1-205 (1)    Ensembl 3981
ncRNA actn1-004 (1)    Ensembl 932
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM actn1 No data available
MARKER RELATIONSHIPS
actn1 Contained in: [BAC] DKEY-22K11 (1) (order this)
actn1 Encodes: [EST] wz13285
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001168286 (1) 3688 nt
Genomic GenBank:CR361558 (1) 204631 nt Blast at MegaBLAST
Polypeptide UniProtKB:B8JHU4 (1) 902 aa
Sequence Information (all 27)
ORTHOLOGY for actn1 ( Chr: 13 )
CITATIONS (23)