ZFIN ID: ZDB-GENE-081110-1
Gene Name: RAS (RAD and GEM)-like GTP binding 2
Gene Symbol: rem2    Nomenclature History

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Previous Name: si:ch211-119o8.5

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 2 Mapping Details/Browsers
Description: Exhibits calcium channel regulator activity. Involved in dopaminergic neuron differentiation. Predicted to localize to plasma membrane. Is expressed in eye and optic tectum. Orthologous to human REM2 (RRAD and GEM like GTPase 2).
Genome Resources: Alliance (1),  Gene:798285 (1),  Ensembl(GRCz11):ENSDARG00000074064 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la023672Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa38348 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-rem2 N/A 1
    DISEASE ASSOCIATED WITH rem2 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH rem2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process dopaminergic neuron differentiation (more)
    Cellular Component membrane (more)
    Molecular Function calcium channel regulator activity (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA rem2-201 (1)    Ensembl 1569
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM rem2 No data available
    MARKER RELATIONSHIPS
    rem2 Contained in: [BAC] CH211-119O8 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001123046 (1) 1569 nt
    Genomic GenBank:AL953896 (1) 158018 nt
    Select Tool
    Polypeptide UniProtKB:A0A2R8QLU3 (1) 309 aa
    Sequence Information (all 8)
    ORTHOLOGY for rem2 ( Chr: 2 )
    CITATIONS (21)