ZFIN ID: ZDB-GENE-081107-54
Gene Name: golgi brefeldin A resistant guanine nucleotide exchange factor 1
Gene Symbol: gbf1    Nomenclature History

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Previous Names: sb:eu951, si:dkey-183c23.1

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 13 Mapping Details/Browsers
Description: Predicted to have ARF guanyl-nucleotide exchange factor activity. Predicted to be involved in regulation of ARF protein signal transduction. Is expressed in head. Orthologous to human GBF1 (golgi brefeldin A resistant guanine nucleotide exchange factor 1).
Genome Resources: Alliance (1),  Gene:566350 (1),  Ensembl(GRCz11):ENSDARG00000027016 (2)
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2005 [eu951]
Wild-type Stages, Structures: Cleavage:8-cell (1.25h-1.5h) to Hatching:Long-pec (48.0h-60.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa9693 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa12707 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa14258 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa18494 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • tsu3994 Point Mutation Exon 23 Nonsynonymous ENU
  • China Zebrafish Resource Center (CZRC) (order this)
  • tsucd7 Small Deletion Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • tsuci20 Indel Unknown Unknown CRISPR
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-gbf1 1
    MO1-gbf1 N/A 1
    DISEASE ASSOCIATED WITH gbf1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH gbf1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process regulation of ARF protein signal transduction (more)
    Molecular Function ARF guanyl-nucleotide exchange factor activity (more)
    GO Terms (all 2)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA gbf1-202 (1)    Ensembl 9522
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM gbf1 No data available
    MARKER RELATIONSHIPS
    gbf1 Contained in: [BAC] CH73-343M8 (1), DKEY-98E8 (1) (order this), DKEY-183C23 (1) (order this), DKEY-196H17 (1) (order this)
    gbf1 Encodes: [EST] eu951 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:XM_009307103 (1)
    Genomic GenBank:CR626878 (1) 201749 nt Blast at MegaBLAST
    Polypeptide UniProtKB:A0A286Y9X1 (1) 1862 aa
    Sequence Information (all 24)
    ORTHOLOGY for gbf1 ( Chr: 13 )
    CITATIONS (15)