Gene

smg6

ID
ZDB-GENE-081107-52
Name
SMG6 nonsense mediated mRNA decay factor
Symbol
smg6 Nomenclature History
Previous Names
  • si:dkey-16f21.2
Type
protein_coding_gene
Location
Chr: 10 Mapping Details/Browsers
Description
Predicted to have telomerase RNA binding activity and telomeric DNA binding activity. Involved in chordate embryonic development and nuclear-transcribed mRNA catabolic process, nonsense-mediated decay. Predicted to localize to cytoplasm and telomerase holoenzyme complex. Orthologous to human SMG6 (SMG6 nonsense mediated mRNA decay factor).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Wittkopp et al., 2009
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With smg6 Human Ortholog
No data available
Associated With smg6 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR002716 PIN domain
Domain IPR018834 DNA/RNA-binding domain, Est1-type
Domain IPR019458 Telomerase activating protein Est1
Homologous_superfamily IPR011990 Tetratricopeptide-like helical domain superfamily
Homologous_superfamily IPR029060 PIN-like domain superfamily
Domain Details Per Protein
Protein Length DNA/RNA-binding domain, Est1-type PIN domain PIN-like domain superfamily Telomerase activating protein Est1 Tetratricopeptide-like helical domain superfamily
UniProtKB:C5J7W9 427
UniProtKB:A0A0R4IZ84 1544
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations