ZFIN ID: ZDB-GENE-081107-30
Gene Name: protein kinase domain containing, cytoplasmic a
Gene Symbol: pkdcca    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: si:ch211-239i4.3 (1), vlk (1)

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 13 Mapping Details/Browsers
Description: Predicted to have ATP binding activity and non-membrane spanning protein tyrosine kinase activity. Predicted to be involved in protein phosphorylation. Predicted to localize to integral component of membrane. Is expressed in eye; fin bud; and pharyngeal arch 3-7. Orthologous to human PKDCC (protein kinase domain containing, cytoplasmic).
Genome Resources: Alliance (1),  Gene:559418 (1),  Ensembl(GRCz11):ENSDARG00000035161 (1)
GENE EXPRESSION
All Expression Data: Fig. S4 from Melvin et al., 2013
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Hatching:Long-pec (48.0h-60.0h)
 
High Throughput Expression: Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la027423Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa9725 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa15357 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH pkdcca HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Rhizomelic limb shortening with dysmorphic features 618821
    DISEASE ASSOCIATED WITH pkdcca VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process phosphorylation (more)
    Cellular Component integral component of membrane (more)
    Molecular Function ATP binding (more)
    GO Terms (all 9)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA pkdcca-202 (1)    Ensembl 1178
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM pkdcca No data available
    MARKER RELATIONSHIPS
    pkdcca Contained in: [BAC] CH211-226D5, CH211-239I4 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001161598 (1) 1693 nt
    Genomic RefSeq:NW_018394861 (1) Blast at MegaBLAST
    Polypeptide UniProtKB:A0A2R8QL49 (1) 516 aa
    Sequence Information (all 15)
    ORTHOLOGY for pkdcca ( Chr: 13 )
    CITATIONS (19)