ZFIN ID: ZDB-GENE-081105-56
Gene Name: lysine (K)-specific demethylase 6A
Gene Symbol: kdm6a
Sequence Ontology ID : SO:0000704

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Previous Name: si:ch211-222m21.1

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(Including Attributions)
Location: Chr: 9 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Larval:Day 4 (96.0h-120.0h)
  brain, ethmoid cartilage, otic vesicle, pharyngeal arch 1 (all 7) expand
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la010166Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la026932Tg Transgenic Insertion Unknown Unknown DNA
    la026933Tg Transgenic Insertion Unknown Unknown DNA
    la029585Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa7197 Point Mutation Unknown Premature Stop ENU
    sa17907 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa34686 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • Targeting reagents: CRISPR1-kdm6a (2), MO1-kdm6a (1), MO2-kdm6a (1), MO3-kdm6a (1), MO4-kdm6a (1)
    PHENOTYPE
    Data: 9 figures from 4 publications
    Observed in: brain, brain development, ceratobranchial cartilage, ceratohyal cartilage (all 28) expand
    DISEASE ASSOCIATED WITH kdm6a HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Kabuki syndrome Kabuki syndrome 2 300867
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process brain development (more)
    Molecular Function histone demethylase activity (H3-K27 specific) (more)
    GO Terms (all 9)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR003347 (1)
  • InterPro:IPR011990 (1)
  • InterPro:IPR013026 (1)
  • InterPro:IPR019734 (1)
  • InterPro:IPR029516 (1)
  • PROSITE:PS50005 (1)
  • PROSITE:PS50293 (1)
  • PROSITE:PS51184 (1)
  • Pfam:PF02373 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA kdm6a-001 (1) 5041
    ncRNA kdm6a-002 (1) 847
     Withdrawn Transcriptsextinct
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM kdm6a No data available
    MARKER RELATIONSHIPS
    kdm6aContained in: [BAC] CH73-147F11 (1) (order this), CH211-222M21 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_005167794 (1) 5812bp
    Genomic GenBank:BX572627 (1) 209758bp Blast at MegaBLAST
    Polypeptide UniProtKB:F1Q597 (1) 1452aa
    Sequence Clusters UniGene:107641 (1)
    Sequence Information (all 18)
    OTHER kdm6a GENE PAGES
  • Alliance (1)
  • Gene:569277 (1)
  • VEGA:OTTDARG00000029362 (1)
  • Ensembl(GRCz10):ENSDARG00000061759 (1)
  • ORTHOLOGY for kdm6a (Chr: 9)
    CITATIONS (22)