Gene

hsd3b1

ID
ZDB-GENE-081105-30
Name
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
Symbol
hsd3b1 Nomenclature History
Previous Names
  • si:rp71-68n21.10
Type
protein_coding_gene
Location
Chr: 9 Mapping Details/Browsers
Description
Exhibits 3-beta-hydroxy-delta5-steroid dehydrogenase activity. Involved in pigmentation. Human ortholog(s) of this gene implicated in hypertension and hypospadias. Is expressed in brain and endocrine system. Orthologous to several human genes including HSD3B1 (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1).
Genome Resources
Note
This gene is orthologous to both human HSD3B1 and HSD3B2
Comparative Information
Expression
All Expression Data
10 figures from 6 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Lin et al., 2015
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With hsd3b1 Human Ortholog
No data available
Associated With hsd3b1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR002225 3-beta hydroxysteroid dehydrogenase/isomerase
Homologous_superfamily IPR036291 NAD(P)-binding domain superfamily
Domain Details Per Protein
Protein Length 3-beta hydroxysteroid dehydrogenase/isomerase NAD(P)-binding domain superfamily
UniProtKB:Q6GMH6 402
UniProtKB:F1QSA2 374
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations