Gene

ednrbb

ID
ZDB-GENE-081105-182
Name
endothelin receptor type Bb
Symbol
ednrbb Nomenclature History
Previous Names
  • ednrb1b
  • si:ch211-72k22.4 (1)
Type
protein_coding_gene
Location
Chr: 9 Mapping Details/Browsers
Description
Predicted to have endothelin receptor activity. Predicted to be involved in several processes, including enteric nervous system development; regulation of blood pressure; and vasoconstriction. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in ABCD syndrome; Hirschsprung's disease; Waardenburg syndrome type 4A; Waardenburg's syndrome; and asthma. Orthologous to human EDNRB (endothelin receptor type B).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Tilghman et al., 2019
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ednrbb Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
ABCD syndrome Alliance ABCD syndrome 600501
Waardenburg syndrome type 4A Alliance Waardenburg syndrome, type 4A 277580
{Hirschsprung disease, susceptibility to, 2} 600155
Associated With ednrbb Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR017452 GPCR, rhodopsin-like, 7TM
Family IPR000276 G protein-coupled receptor, rhodopsin-like
Family IPR000499 Endothelin receptor family
Family IPR001112 Endothelin receptor B
Domain Details Per Protein
Protein Length Endothelin receptor B Endothelin receptor family GPCR, rhodopsin-like, 7TM G protein-coupled receptor, rhodopsin-like
UniProtKB:F1QPV3 363
UniProtKB:F8W4E0 365
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations