ZFIN ID: ZDB-GENE-081105-129
Gene Name: sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6Bb
Gene Symbol: sema6bb    Nomenclature History

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Previous Name: si:ch211-87a2.1

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 8 Mapping Details/Browsers
Description: Predicted to have chemorepellent activity and semaphorin receptor binding activity. Predicted to be involved in several processes, including negative regulation of axon extension involved in axon guidance; neural crest cell migration; and semaphorin-plexin signaling pathway. Predicted to localize to the extracellular space and integral component of plasma membrane. Is expressed in fin bud; head mesenchyme; nervous system; and otic vesicle. Orthologous to human SEMA6B (semaphorin 6B).
Genome Resources: Alliance (1),  Ensembl(GRCz11):ENSDARG00000061976 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa9705 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-sema6bb
    2
    CRISPR2-sema6bb
    2
    CRISPR3-sema6bb
    2
    CRISPR4-sema6bb
    2
    CRISPR5-sema6bb
    2
    CRISPR6-sema6bb
    2
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH sema6bb HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH sema6bb VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process negative chemotaxis (more)
    Cellular Component integral component of membrane (more)
    Molecular Function semaphorin receptor binding (more)
    GO Terms (all 11)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR001627 Sema domain
    Homologous_superfamily IPR015943 WD40/YVTN repeat-like-containing domain superfamily
    Family IPR027231 Semaphorin
    Homologous_superfamily IPR036352 Sema domain superfamily
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA sema6bb-201 (1)    Ensembl 1947
    Browsers: EnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM sema6bb No data available
    MARKER RELATIONSHIPS
    sema6bb Contained in: [BAC] CH211-87A2 (1), DKEY-192C10 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    Genomic GenBank:CR376858 (1) 165716 bp
    Select Tool
    Polypeptide UniProtKB:B8JHX0 (1) 639 aa
    Sequence Information (all 3)
    ORTHOLOGY for sema6bb ( Chr: 8 )
    CITATIONS (15)