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ZIRC
ZFIN ID: ZDB-GENE-081105-114
Gene Name: collagen, type IV, alpha 1
Gene Symbol: col4a1
Sequence Ontology ID : SO:0001217

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Previous Names: fj65e07, im:7157877 (1), si:ch211-174g17.1 (1), wu:fj65e07 (1)

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(Including Attributions)
Location: Chr: 9 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have extracellular matrix structural constituent. Predicted to localize to the collagen trimer. Human ortholog(s) of this gene implicated in COL4A1-related familial vascular  ...
GENE EXPRESSION
All Expression Data: 9 figures from 4 publications
Directly Submitted Expression Data: 6 figures (20 images) from Thisse et al., 2004 [IMAGE:7157877]
Wild-type Stages, Structures: Segmentation:1-4 somites (10.33h-11.66h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
col4a1_unrecovered Point Mutation Unknown Unknown ENU
fh336 Point Mutation Unknown Unknown ENU
sa16923 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa21437 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa27345 Point Mutation Unknown Premature Stop ENU
    sa34559 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa34560 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa41357 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa45346 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • st93 Small Deletion Unknown Unknown TALEN
    Targeting reagents:
    DISEASE ASSOCIATED WITH col4a1 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    COL4A1-related familial vascular leukoencephalopathy Brain small vessel disease with or without ocular anomalies 175780
    Angiopathy, hereditary, with nephropathy, aneurysms, and muscle cramps 611773
    Microangiopathy and leukoencephalopathy, pontine, autosomal dominant 618564
    ?Retinal arteries, tortuosity of 180000
    {Hemorrhage, intracerebral, susceptibility to} 614519
    DISEASE ASSOCIATED WITH col4a1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process growth plate cartilage chondrocyte morphogenesis (more)
    Cellular Component collagen trimer (more)
    Molecular Function extracellular matrix structural constituent (more)
    GO Terms (all 6)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA col4a1-201 (1) 5961
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM col4a1 No data available
    MARKER RELATIONSHIPS
    col4a1 Contained in: [BAC] CH73-182O2 (1) (order this), CH211-174G17 (1) (order this)
    col4a1 Encodes: [EST] fj65e07, IMAGE:7157877 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_688948 (1) 7341 bp
    Genomic GenBank:FP103004 (1) 87932 bp
    Select Tool
    Polypeptide UniProtKB:F1Q8S5 (1) 1583 aa
    Sequence Clusters UniGene:117044 (1)
    Sequence Information (all 30)
    ORTHOLOGY for col4a1 ( Chr: 9 )
    CITATIONS (27)