ZFIN ID: ZDB-GENE-081105-114
Gene Name: collagen, type IV, alpha 1
Gene Symbol: col4a1
Previous Names: fj65e07, im:7157877 (1), si:ch211-174g17.1 (1), wu:fj65e07 (1)
Location: Chr: 9 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 9 figures from 4 publications
Directly Submitted Expression Data: 6 figures (20 images) from Thisse et al., 2004 [IMAGE:7157877]
Wild-type Stages, Structures: Segmentation:1-4 somites (10.33h-11.66h) to Adult (90d-730d, breeding adult)
  cardiovascular system, hypodermis, paraxial mesoderm, vasculature basement membrane (all 5) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
col4a1_unrecovered Point Mutation Unknown Unknown ENU
fh336 Point Mutation Unknown Unknown ENU
sa16923 Point Mutation Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa21437 Point Mutation Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa34559 Point Mutation Unknown Unknown ENU
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH col4a1 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    porencephaly Porencephaly 1 175780
    {Hemorrhage, intracerebral, susceptibility to} 614519
    ?Retinal arteries, tortuosity of 180000
    Angiopathy, hereditary, with nephropathy, aneurysms, and muscle cramps 611773
    Brain small vessel disease with or without ocular anomalies 607595
    GENE ONTOLOGY
    Ontology GO Term
    Cellular Component collagen trimer (more)
    Molecular Function extracellular matrix structural constituent (more)
    GO Terms (all 4)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001442 (1)
  • InterPro:IPR008160 (1)
  • InterPro:IPR016187 (1)
  • PROSITE:PS51403 (1)
  • Pfam:PF01391 (1)
  • Pfam:PF01413 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA col4a1-001 (1) 5961
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYSNo data available
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM col4a1 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    col4a1Contained in: [BAC] CH73-182O2 (1) (order this), CH211-174G17 (1) (order this)
    col4a1Encodes: [EST] fj65e07, IMAGE:7157877 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_688948 (1) 5456bp
    Genomic GenBank:FP103004 (1) 87932bp
    Select Tool
    Polypeptide UniProtKB:F1Q8S5 (1) 1583aa
    Sequence Clusters UniGene:117044 (1)
    Sequence Information (all 29)
    OTHER col4a1 GENE PAGES
  • Gene:554269 (1)
  • VEGA:OTTDARG00000029009 (1)
  • Ensembl(GRCz10):ENSDARG00000055009 (1)
  • ORTHOLOGY for col4a1 (Chr: 9)
    Species Symbol Chromosome Accession # Evidence
    Human COL4A1 13
  • Gene:1282
  • OMIM:120130
  • HGNC:2202
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Mouse Col4a1 8
  • MGI:88454
  • Gene:12826
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (21)