ZFIN ID: ZDB-GENE-081105-114
Gene Name: collagen, type IV, alpha 1
Gene Symbol: col4a1
Previous Names: fj65e07, im:7157877 (1), si:ch211-174g17.1 (1), wu:fj65e07 (1)
Location: Chr: 9 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 9 figures from 4 publications
Directly Submitted Expression Data: 6 figures (20 images) from Thisse et al., 2004 [IMAGE:7157877]
Wild-type Stages, Structures: Segmentation:1-4 somites (10.33h-11.66h) to Adult (90d-730d, breeding adult)
  cardiovascular system, hypodermis, paraxial mesoderm, vasculature basement membrane (all 5) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS 
Allele Type Mutagen Suppliers
col4a1_unrecovered Point Mutation ENU
fh336 Point Mutation ENU
sa16923 Point Mutation ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa21437 Point Mutation ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH col4a1 HUMAN ORTHOLOG 
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    porencephaly Porencephaly 1 175780
    Brain small vessel disease with or without ocular anomalies 607595
    ?Retinal arteries, tortuosity of 180000
    Angiopathy, hereditary, with nephropathy, aneurysms, and muscle cramps 611773
    {Hemorrhage, intracerebral, susceptibility to} 614519
    GENE ONTOLOGY 
    Ontology GO Term
    Cellular Component collagen trimer (more)
    Molecular Function extracellular matrix structural constituent (more)
    GO Terms (all 4)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001442 (1)
  • InterPro:IPR008160 (1)
  • InterPro:IPR016187 (1)
  • PROSITE:PS51403 (1)
  • Pfam:PF01391 (1)
  • Pfam:PF01413 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA col4a1-001 (1) 5961
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM col4a1 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS 
    col4a1Contained in: [BAC] CH73-182O2 (1) (order this), CH211-174G17 (1) (order this)
    col4a1Encodes: [EST] fj65e07, IMAGE:7157877 (1) (order this)
    SEQUENCE INFORMATION 
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_688948 (1) 5250bp
    Genomic GenBank:FP103004 (1) 87932bp
    Select Tool
    Polypeptide UniProtKB:F1Q8S5 (1) 1583aa
    Sequence Clusters UniGene:117044 (1)
    Sequence Information (all 28)
    OTHER col4a1 GENE PAGES 
  • Gene:554269 (1)
  • VEGA:OTTDARG00000029009 (1)
  • Ensembl(GRCz10):ENSDARG00000055009 (1)
  • ORTHOLOGY for col4a1 (Chr: 9) 
    Species Symbol Chromosome Accession # Evidence
    Human COL4A1 13
  • Gene:1282
  • OMIM:120130
  • HGNC:2202
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Mouse Col4a1 8
  • MGI:88454
  • Gene:12826
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (20)