Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-081105-114
Gene Name: collagen, type IV, alpha 1
Gene Symbol: col4a1
Previous Names: fj65e07, im:7157877 (1), si:ch211-174g17.1 (1), wu:fj65e07 (1)
Nomenclature History
GENE EXPRESSION
All Expression Data: 8 figures from 3 publications
Directly Submitted Expression Data: 6 figures (20 images) from Thisse et al., 2004 [IMAGE:7157877]
Wild-type Stages, Structures: Segmentation:1-4 somites (10.33h-11.66h) to Adult (90d-730d, breeding adult)
  cardiovascular system, hypodermis, paraxial mesoderm, whole organism
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Mutant lines: 2 genotypes
Alleles: col4a1_unrecovered, fh336, sa16923, sa21437
PHENOTYPE
Phenotype of Human Orthologue OMIM Phenotype ID
Angiopathy, hereditary, with nephropathy, aneurysms, and muscle 611773
Brain small vessel disease with Axenfeld-Rieger anomaly 607595
Brain small vessel disease with hemorrhage 607595
Porencephaly 1 175780
{Hemorrhage, intracerebral, susceptibility to} 614519
GENE ONTOLOGY
Ontology GO Term
Cellular Component collagen (more)
Molecular Function extracellular matrix structural constituent (more)
GO Terms (all 2)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001442 (1)
  • InterPro:IPR008160 (1)
  • InterPro:IPR016187 (1)
  • PROSITE:PS51403 (1)
  • Pfam:PF01391 (1)
  • Pfam:PF01413 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA col4a1-001 (1) 5961
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    CONSTRUCTS WITH SEQUENCES FROM col4a1 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    col4a1 Contained in: [BAC] CH73-182O2 (1) (order this), CH211-174G17 (1) (order this)
    col4a1 Encodes: [EST] fj65e07, IMAGE:7157877 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_688948 (1) 9457 bp
    Genomic GenBank:FP103004 (1) 87932 bp
    Select Tool
    Polypeptide UniProtKB:F1QG79 (1) 1644 aa
    Sequence Clusters UniGene:44023 (1)
    Sequence Information (all 28)
    OTHER col4a1 GENE PAGES
  • Gene:554269 (1)
  • VEGA:OTTDARG00000029009 (1)
  • Ensembl(Zv9):ENSDARG00000055009 (1)
  • MAPPING INFORMATION
    Chr: 9 Details
    ORTHOLOGY
      Evidence
    Species Symbol Chromosome (Position) Accession # AA CL
    Zebrafish col4a1 9  
    Human COL4A1 13 (13q34)
  • OMIM:120130
  • Gene:1282
  • Mouse Col4a1 8 ( 5.53 cM)
  • MGI:88454
  • Gene:12826
  • CITATIONS (17)