ZFIN ID: ZDB-GENE-081105-114
Gene Name: collagen, type IV, alpha 1
Gene Symbol: col4a1
Previous Names: fj65e07, im:7157877 (1), si:ch211-174g17.1 (1), wu:fj65e07 (1)
Location: Chr: 9   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 8 figures from 3 publications
Directly Submitted Expression Data: 6 figures (20 images) from Thisse et al., 2004 [IMAGE:7157877]
Wild-type Stages, Structures: Segmentation:1-4 somites (10.33h-11.66h) to Adult (90d-730d, breeding adult)
  cardiovascular system, hypodermis, paraxial mesoderm, whole organism
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Mutant lines: 2 Genotypes

Allele Type Mutagen Suppliers
col4a1_unrecovered Point Mutation ENU
  • Moens Lab (order this)
  • fh336 Point Mutation ENU
  • Moens Lab (order this)
  • sa16923 Point Mutation ENU
    sa21437 Point Mutation ENU
    PHENOTYPE
    Phenotype of Human Orthologue OMIM Phenotype ID
    Angiopathy, hereditary, with nephropathy, aneurysms, and muscle cramps 611773
    Brain small vessel disease with or without ocular anomalies 607595
    Porencephaly 1 175780
    ?Retinal arteries, tortuosity of 180000
    {Hemorrhage, intracerebral, susceptibility to} 614519
    GENE ONTOLOGY
    Ontology GO Term
    Cellular Component collagen trimer (more)
    Molecular Function extracellular matrix structural constituent (more)
    GO Terms (all 2)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001442 (1)
  • InterPro:IPR008160 (1)
  • InterPro:IPR016187 (1)
  • PROSITE:PS51403 (1)
  • Pfam:PF01391 (1)
  • Pfam:PF01413 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA col4a1-001 (1) 5961
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM col4a1 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    col4a1 Contained in: [BAC] CH73-182O2 (1) (order this), CH211-174G17 (1) (order this)
    col4a1 Encodes: [EST] fj65e07, IMAGE:7157877 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_688948 (1) 5250 bp
    Genomic GenBank:FP103004 (1) 87932 bp
    Select Tool
    Polypeptide UniProtKB:F1QG79 (1) 1644 aa
    Sequence Clusters UniGene:117044 (1)
    Sequence Information (all 28)
    OTHER col4a1 GENE PAGES
  • Gene:554269 (1)
  • VEGA:OTTDARG00000029009 (1)
  • Ensembl(Zv9):ENSDARG00000055009 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish col4a1 9  
    Human COL4A1 13 (13q34)
  • OMIM:120130
  • Gene:1282
  • Mouse Col4a1 8 ( 5.53 cM)
  • MGI:88454
  • Gene:12826
  • Orthology Details
    CITATIONS (18)