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General Information
ZIRC
ZFIN ID: ZDB-GENE-081104-519
Gene Name: cytochrome P450, family 27, subfamily A, polypeptide 7
Gene Symbol: cyp27a7    Nomenclature History

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Previous Name: si:dkeyp-68f9.9

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 9 Mapping Details/Browsers
Description: Predicted to have heme binding activity; iron ion binding activity; and oxidoreductase activity. Predicted to be involved in oxidation-reduction process. Human ortholog(s) of this gene implicated in cerebrotendinous xanthomatosis. Orthologous to human CYP27A1 (cytochrome P450 family 27 subfamily A member 1).
Genome Resources: Alliance (1),  Gene:402831 (1),  Ensembl(GRCz11):ENSDARG00000033802 (2)
GENE EXPRESSION
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa9857 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa18959 Point Mutation Unknown Premature Stop ENU
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH cyp27a7 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH cyp27a7 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process oxidation-reduction process (more)
    Molecular Function heme binding (more)
    GO Terms (all 7)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA cyp27a7-201 (1)    Ensembl 2374
    ncRNA cyp27a7-002 (1)    Ensembl 881
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM cyp27a7 No data available
    MARKER RELATIONSHIPS
    cyp27a7 Contained in: [BAC] DKEYP-68F9 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_002663399 (1) 2519 bp
    Genomic GenBank:BX001051 (1) 213486 bp Blast at MegaBLAST
    Polypeptide UniProtKB:Q7SXE6 (1) 531 aa
    Sequence Clusters UniGene:144802 (1)
    Sequence Information (all 10)
    ORTHOLOGY for cyp27a7 ( Chr: 9 )
    CITATIONS (15)