ZFIN ID: ZDB-GENE-081104-470
Gene Name: adenylate cyclase 5
Gene Symbol: adcy5    Nomenclature History

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Previous Names: ac5 (1), fan (1), fantasma (1), si:dkey-178j17.2, si:dkeyp-60a7.2

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 9 Mapping Details/Browsers
Description: Predicted to have adenylate cyclase activity. Involved in regulation of protein phosphorylation and response to ethanol. Predicted to localize to the integral component of plasma membrane. Is expressed in brain; head; and heart. Orthologous to human ADCY5 (adenylate cyclase 5).
Genome Resources: Alliance (1),  Gene:562619 (1),  Ensembl(GRCz11):ENSDARG00000091342 (2)
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Wild-type Stages, Structures: Cleavage:4-cell (1.0h-1.25h) to Larval:Days 21-29 (21d-30d, 7.8mm, 10 teeth)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
s2000 Point Mutation Unknown Unknown ENU
sa45365 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-adcy5 N/A 1
    PHENOTYPE
    Data: Fig. 6 from Peng et al., 2009
    Observed in:
    DISEASE ASSOCIATED WITH adcy5 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Dyskinesia, familial, with facial myokymia 606703
    DISEASE ASSOCIATED WITH adcy5 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process regulation of protein phosphorylation (more)
    Cellular Component integral component of membrane (more)
    Molecular Function adenylate cyclase activity (more)
    GO Terms (all 17)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Conserved_site IPR018297 Adenylyl cyclase class-4/guanylyl cyclase, conserved site
    Domain IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase
    Domain IPR009398 Adenylate cyclase, conserved domain
    Domain IPR032628 Adenylate cyclase, N-terminal
    Family IPR030672 Adenylate cyclase
    Homologous_superfamily IPR029787 Nucleotide cyclase
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA adcy5-201 (1)    Ensembl 3814
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM adcy5 No data available
    MARKER RELATIONSHIPS
    adcy5 Contained in: [BAC] CH211-92C19 (1), DKEYP-60A7 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001171585 (1) 3829 nt
    Genomic GenBank:CU896658 (1) 189733 nt
    Select Tool
    Polypeptide UniProtKB:D2CFN3 (1) 1186 aa
    Sequence Information (all 10)
    ORTHOLOGY for adcy5 ( Chr: 9 )
    CITATIONS (24)