Gene

hbaa2

ID

ZDB-GENE-081104-38

Name

hemoglobin, alpha adult 2

Symbol

hbaa2 Nomenclature History

Previous Names

si:ch211-5k11.6
si:xx-187g17.5 (1)
si:xx-by187g17.5
zgc:112086

Type

protein_coding_gene

Location

Chr: 3 Mapping Details/Browsers

Description

Predicted to contribute to haptoglobin binding activity and peroxidase activity. Predicted to be involved in hydrogen peroxide catabolic process. Predicted to localize to haptoglobin-hemoglobin complex and hemoglobin complex. Human ortholog(s) of this gene implicated in Heinz body anemia; alpha thalassemia; familial erythrocytosis 7; and hemoglobin H disease. Orthologous to several human genes including HBA2 (hemoglobin subunit alpha 2) and HBZ (hemoglobin subunit zeta).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

MGC:112086 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With hbaa2 Human Ortholog

No data available

Associated With hbaa2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000971	Globin
Family	IPR002338	Hemoglobin, alpha-type
Family	IPR002339	Hemoglobin, pi
Homologous_superfamily	IPR009050	Globin-like superfamily
Homologous_superfamily	IPR012292	Globin/Protoglobin