ZFIN ID: ZDB-GENE-081104-38
Gene Name: hemoglobin, alpha adult 2
Gene Symbol: hbaa2    Nomenclature History

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Previous Names: si:ch211-5k11.6, si:xx-187g17.5 (1), si:xx-by187g17.5, zgc:112086

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 3 Mapping Details/Browsers
Description: Predicted to contribute to haptoglobin binding activity and peroxidase activity. Predicted to be involved in hydrogen peroxide catabolic process. Predicted to localize to haptoglobin-hemoglobin complex and hemoglobin complex. Human ortholog(s) of this gene implicated in Heinz body anemia; alpha thalassemia; familial erythrocytosis 7; and hemoglobin H disease. Orthologous to several human genes including HBA2 (hemoglobin subunit alpha 2) and HBZ (hemoglobin subunit zeta).
Genome Resources: Alliance (1),  Gene:497166 (1),  Ensembl(GRCz11):ENSDARG00000069735 (1)
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:112086]
Wild-type Stages, Structures: Segmentation:14-19 somites (16.0h-19.0h) to Pharyngula:Prim-5 (24.0h-30.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa26158 Point Mutation Unknown Premature Stop ENU
PHENOTYPE No data available
DISEASE ASSOCIATED WITH hbaa2 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH hbaa2 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process oxygen transport (more)
Cellular Component hemoglobin complex (more)
Molecular Function heme binding (more)
GO Terms (all 12)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA hbaa2-201 (1)    Ensembl 564
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM hbaa2 No data available
MARKER RELATIONSHIPS
hbaa2 Contained in: [BAC] CH211-5K11 (1), XX-BY187G17
hbaa2 Encodes: [cDNA] MGC:112086 (1), MGC:191455 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001013461 (1) 573 nt
Genomic GenBank:AL929176 100902 nt
Select Tool
Polypeptide UniProtKB:Q5BJC7 (1) 143 aa
Sequence Information (all 17)
ORTHOLOGY for hbaa2 ( Chr: 3 )
CITATIONS (23)