ZFIN ID: ZDB-GENE-081104-33
Gene Name: FYVE, RhoGEF and PH domain containing 1
Gene Symbol: fgd1
Previous Name: si:dkey-242k1.1 (1)
Location: Chr: 8 Details
Nomenclature History
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTSNo data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH fgd1 HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
Aarskog-Scott syndrome Aarskog-Scott syndrome 305400
Mental retardation, X-linked syndromic 16 305400
GENE ONTOLOGY
Ontology GO Term
Biological Process regulation of Rho protein signal transduction (more)
Molecular Function Rho guanyl-nucleotide exchange factor activity (more)
GO Terms (all 3)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000219 (1)
  • InterPro:IPR000306 (1)
  • InterPro:IPR001849 (1)
  • InterPro:IPR011011 (1)
  • InterPro:IPR011993 (1)
  • InterPro:IPR013083 (1)
  • InterPro:IPR017455 (1)
  • PROSITE:PS50003 (1)
  • PROSITE:PS50010 (1)
  • PROSITE:PS50178 (1)
  • Pfam:PF00169 (1)
  • Pfam:PF00621 (1)
  • Pfam:PF01363 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA ottdart00000051857 (1) 2340
    antisense ottdart00000059734 (1) 934
     Withdrawn Transcriptsextinct
    GENE PRODUCT DESCRIPTION
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM fgd1 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    fgd1Contained in: [BAC] DKEY-242K1 (1) (order this)
    [Fosmid] CH1073-386N8 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_683702 (1) 3704bp
    Genomic GenBank:CR931813 (1) 150062bp
    Select Tool
    Polypeptide UniProtKB:F1R601 (1) 839aa
    Sequence Clusters UniGene:115997 (1)
    Sequence Information (all 8)
    OTHER fgd1 GENE PAGES
  • Gene:560305 (1)
  • VEGA:OTTDARG00000036422 (1)
  • VEGA:OTTDARG00000041422 (1)
  • Ensembl(GRCz10):ENSDARG00000100402 (1)
  • ORTHOLOGY for fgd1 (Chr: 8)
    Species Symbol Chromosome Accession # Evidence
    Human FGD1 X
  • Gene:2245
  • OMIM:300546
  • HGNC:3663
  • Amino acid sequence comparison (1)
    Mouse Fgd1 X
  • MGI:104566
  • Gene:14163
  • Amino acid sequence comparison (1)
    Download Curated Orthology
    CITATIONS (11)