Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-081104-33
Gene Name: FYVE, RhoGEF and PH domain containing 1
Gene Symbol: fgd1
Previous Name: si:dkey-242k1.1 (1)
Nomenclature History
GENE EXPRESSION No data available
MUTANTS AND TARGETED KNOCKDOWNS No data available
PHENOTYPE
Phenotype of Human Orthologue OMIM Phenotype ID
Aarskog-Scott syndrome 305400
Mental retardation, X-linked syndromic 16 305400
GENE ONTOLOGY
Ontology GO Term
Biological Process regulation of Rho protein signal transduction (more)
Molecular Function Rho guanyl-nucleotide exchange factor activity (more)
GO Terms (all 3)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000219 (1)
  • InterPro:IPR000306 (1)
  • InterPro:IPR001849 (1)
  • InterPro:IPR011011 (1)
  • InterPro:IPR011993 (1)
  • InterPro:IPR013083 (1)
  • InterPro:IPR017455 (1)
  • PROSITE:PS50003 (1)
  • PROSITE:PS50010 (1)
  • PROSITE:PS50178 (1)
  • Pfam:PF00169 (1)
  • Pfam:PF00621 (1)
  • Pfam:PF01363 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    antisense dkey-242k1.9-001 (1) 934
    mRNA ottdart00000051857 (1) 2340
     Withdrawn Transcriptsextinct
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    CONSTRUCTS WITH SEQUENCES FROM fgd1 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    fgd1 Contained in: [BAC] DKEY-242K1 (1)
    [Fosmid] CH1073-386N8 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_683702 (1) 3107 bp
    Genomic GenBank:CR931813 (1) 150062 bp
    Select Tool
    Polypeptide UniProtKB:F1R601 (1) 839 aa
    Sequence Clusters UniGene:115997 (1)
    Sequence Information (all 9)
    OTHER fgd1 GENE PAGES
  • Gene:560305 (1)
  • VEGA:OTTDARG00000036422 (1)
  • Ensembl(Zv9):ENSDARG00000017473 (1)
  • MAPPING INFORMATION
    Chr: 8 Details
    ORTHOLOGY
      Evidence
    Species Symbol Chromosome (Position) Accession # AA
    Zebrafish fgd1 8  
    Human FGD1 X (Xp11.21)
  • OMIM:300546
  • Gene:2245
  • Mouse Fgd1 X ( 68.46 cM)
  • MGI:104566
  • Gene:14163
  • CITATIONS (11)