ZFIN ID: ZDB-GENE-081104-305
Gene Name: chordin-like 2
Gene Symbol: chrdl2    Nomenclature History

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Previous Names: Chl (1), sb:eu491, sb:eu494, si:dkey-11j5.7 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 21 Mapping Details/Browsers
Description: Involved in dorsal/ventral pattern formation. Is expressed in hindbrain; midbrain; and tail bud. Human ortholog(s) of this gene implicated in megalocornea. Orthologous to several human genes including CHRDL2 (chordin like 2).
Genome Resources: Alliance (1),  Gene:563085 (1),  Ensembl(GRCz11):ENSDARG00000078916 (2)
GENE EXPRESSION
All Expression Data: 5 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2005 [eu491]
  1 figure (1 image) from Thisse et al., 2005 [eu494]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa25157 Point Mutation Unknown Premature Stop ENU
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-chrdl2 N/A 2
MO2-chrdl2 N/A 1
MO3-chrdl2 N/A 1
DISEASE ASSOCIATED WITH chrdl2 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH chrdl2 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process dorsal/ventral pattern formation (more)
GO Terms (all 1)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA chrdl2-201 (1)    Ensembl 2114
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM chrdl2 No data available
MARKER RELATIONSHIPS
chrdl2 Contained in: [BAC] CH73-149B22 (1), DKEY-11J5 (1) (order this)
chrdl2 Encodes: [EST] eu491 (1), eu494 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001130959 (1) 2123 nt
Genomic GenBank:BX005026 154034 nt
Select Tool
Polypeptide UniProtKB:B4XEZ3 (1) 454 aa
Sequence Information (all 14)
ORTHOLOGY for chrdl2 ( Chr: 21 )
CITATIONS (13)