Gene

cdk12

ID
ZDB-GENE-081104-294
Name
cyclin-dependent kinase 12
Symbol
cdk12 Nomenclature History
Previous Names
  • si:ch73-79d13.1
  • wu:fa01h10
Type
protein_coding_gene
Location
Chr: 19 Mapping Details/Browsers
Description
Predicted to have RNA polymerase II CTD heptapeptide repeat kinase activity; cyclin binding activity; and cyclin-dependent protein serine/threonine kinase activity. Predicted to be involved in phosphorylation of RNA polymerase II C-terminal domain; positive regulation of transcription elongation from RNA polymerase II promoter; and transcription elongation from RNA polymerase II promoter. Predicted to localize to cyclin/CDK positive transcription elongation factor complex. Orthologous to several human genes including CDK12 (cyclin dependent kinase 12).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cdk12 Human Ortholog
No data available
Associated With cdk12 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR008271 Serine/threonine-protein kinase, active site
Binding_site IPR017441 Protein kinase, ATP binding site
Domain IPR000719 Protein kinase domain
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Domain Details Per Protein
Protein Length Protein kinase, ATP binding site Protein kinase domain Protein kinase-like domain superfamily Serine/threonine-protein kinase, active site
UniProtKB:F1R6Y1 1293
UniProtKB:I3IT26 155
UniProtKB:I3ITA7 222
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations