Gene

dnm1a

ID
ZDB-GENE-081104-27
Name
dynamin 1a
Symbol
dnm1a Nomenclature History
Previous Names
  • si:dkey-246l19.2
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to have GTPase activity and microtubule binding activity. Predicted to be involved in several processes, including dynamin family protein polymerization involved in mitochondrial fission; mitochondrial fission; and vesicle-mediated transport in synapse. Predicted to localize to several cellular components, including dendritic spine head; postsynaptic density; and postsynaptic endocytic zone membrane. Human ortholog(s) of this gene implicated in early infantile epileptic encephalopathy 31. Orthologous to human DNM1 (dynamin 1).
Genome Resources
Note
None
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With dnm1a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
early infantile epileptic encephalopathy 31 Alliance Epileptic encephalopathy, early infantile, 31 616346
Associated With dnm1a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR019762 Dynamin, GTPase region, conserved site
Domain IPR001401 Dynamin, GTPase domain
Domain IPR001849 Pleckstrin homology domain
Domain IPR003130 Dynamin GTPase effector
Domain IPR020850 GTPase effector domain
Domain IPR030381 Dynamin-type guanine nucleotide-binding (G) domain
Family IPR022812 Dynamin superfamily
Family IPR027741 Dynamin-1
Homologous_superfamily IPR011993 PH-like domain superfamily
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Domain Details Per Protein
Protein Length Dynamin-1 Dynamin, GTPase domain Dynamin GTPase effector Dynamin, GTPase region, conserved site Dynamin superfamily Dynamin-type guanine nucleotide-binding (G) domain GTPase effector domain PH-like domain superfamily Pleckstrin homology domain P-loop containing nucleoside triphosphate hydrolase
UniProtKB:E4VNZ2 843
UniProtKB:F8W429 852
UniProtKB:A0A0R4IG45 843
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations